249113

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 5239581..5240169 Replicon chromosome
Accession NZ_CP099575
Organism Pseudomonas kermanshahensis strain F8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NG836_RS23545 Protein ID WP_252825351.1
Coordinates 5239581..5239883 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NG836_RS23550 Protein ID WP_027593133.1
Coordinates 5239876..5240169 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG836_RS26960 5235543..5235671 - 129 WP_256214945.1 PA1414 family protein -
NG836_RS23525 (NG836_23525) 5235796..5236689 - 894 WP_252825348.1 LysR family transcriptional regulator -
NG836_RS23530 (NG836_23530) 5236796..5237995 + 1200 WP_252825349.1 YbfB/YjiJ family MFS transporter -
NG836_RS23535 (NG836_23535) 5238024..5238950 - 927 WP_099430143.1 DMT family transporter -
NG836_RS23540 (NG836_23540) 5239056..5239451 - 396 WP_027593132.1 hypothetical protein -
NG836_RS23545 (NG836_23545) 5239581..5239883 + 303 WP_252825351.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NG836_RS23550 (NG836_23550) 5239876..5240169 + 294 WP_027593133.1 putative addiction module antidote protein Antitoxin
NG836_RS23555 (NG836_23555) 5240282..5240554 + 273 WP_099455003.1 hypothetical protein -
NG836_RS23560 (NG836_23560) 5240611..5241972 - 1362 WP_027593135.1 DEAD/DEAH box helicase -
NG836_RS23565 (NG836_23565) 5242077..5243363 + 1287 WP_099455004.1 mechanosensitive ion channel family protein -
NG836_RS23570 (NG836_23570) 5243478..5244413 - 936 WP_252825353.1 AEC family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5231862..5250841 18979


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(22-87)

Antitoxin

Uncharacterized protein HI1420

(8-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11432.12 Da        Isoelectric Point: 10.5383

>T249113 WP_252825351.1 NZ_CP099575:5239581-5239883 [Pseudomonas kermanshahensis]
MKKIESSSFRHWVHGLRDEMARIRIIARINRLMEGLSGDVSAVGHGVSELRIHHGPGYRVYFHQAGDTLVILLCGGDKSS
QRRDIKAAHEILRSWRMQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10517.96 Da        Isoelectric Point: 5.5740

>AT249113 WP_027593133.1 NZ_CP099575:5239876-5240169 [Pseudomonas kermanshahensis]
MTETFFEFDAADYLTTPQAIAQFMSDALETGDASYVAKAVGVVARAKGMSDLAKETGLSREQLYRSFSEHGNPTLKSFLA
VMKALGIDMTAKPHLAH

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References