Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1646864..1647381 Replicon chromosome
Accession NZ_CP099547
Organism Arcanobacterium pinnipediorum strain DSM 28752

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NG665_RS07345 Protein ID WP_252673061.1
Coordinates 1646864..1647118 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NG665_RS07350 Protein ID WP_252673062.1
Coordinates 1647124..1647381 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG665_RS07325 (NG665_07325) 1642178..1643455 - 1278 WP_252673057.1 ABC transporter substrate-binding protein -
NG665_RS07330 (NG665_07330) 1643728..1645557 + 1830 WP_252673058.1 hypothetical protein -
NG665_RS07335 (NG665_07335) 1645644..1646087 - 444 WP_252673059.1 GNAT family N-acetyltransferase -
NG665_RS07340 (NG665_07340) 1646163..1646669 - 507 WP_252673060.1 GNAT family N-acetyltransferase -
NG665_RS07345 (NG665_07345) 1646864..1647118 - 255 WP_252673061.1 Txe/YoeB family addiction module toxin Toxin
NG665_RS07350 (NG665_07350) 1647124..1647381 - 258 WP_252673062.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NG665_RS07355 (NG665_07355) 1647657..1648736 - 1080 WP_252673063.1 redox-regulated ATPase YchF -
NG665_RS07360 (NG665_07360) 1648872..1650092 + 1221 WP_252673064.1 DNA recombination protein RmuC -
NG665_RS07365 (NG665_07365) 1650198..1651304 - 1107 WP_252674106.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10280.73 Da        Isoelectric Point: 9.2456

>T249106 WP_252673061.1 NZ_CP099547:c1647118-1646864 [Arcanobacterium pinnipediorum]
VKYVWDENAWQDYLWWQAHDRKMLKRINLLLKDISRNGNEGIGKPEPLKYELAGYWSRRISDEHRLVFKYTETAVYIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9688.84 Da        Isoelectric Point: 4.8782

>AT249106 WP_252673062.1 NZ_CP099547:c1647381-1647124 [Arcanobacterium pinnipediorum]
MKTMSYSESRAHYADVLKSVVEDREEVIITRKGHDSAVIVSLDDYNSLRETAYLMRSPRNARRLFDAVERLEAGEGTTQP
LLEAE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References