Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 82423..83330 | Replicon | plasmid unnamed1 |
| Accession | NZ_CP099536 | ||
| Organism | Pantoea ananatis strain JT1-188 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | NG826_RS21425 | Protein ID | WP_047713814.1 |
| Coordinates | 82423..82890 (-) | Length | 156 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | NG826_RS21430 | Protein ID | WP_263794345.1 |
| Coordinates | 82887..83330 (-) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NG826_RS21405 (NG826_21365) | 77811..78044 | - | 234 | WP_072208328.1 | DUF333 domain-containing protein | - |
| NG826_RS21410 (NG826_21370) | 78132..78704 | + | 573 | WP_014598338.1 | NADPH-dependent FMN reductase | - |
| NG826_RS21415 (NG826_21375) | 78766..79701 | - | 936 | WP_028722485.1 | flagellin | - |
| NG826_RS21420 (NG826_21380) | 80384..81778 | - | 1395 | WP_028722484.1 | flagellar filament capping protein FliD | - |
| NG826_RS21425 (NG826_21385) | 82423..82890 | - | 468 | WP_047713814.1 | RES family NAD+ phosphorylase | Toxin |
| NG826_RS21430 (NG826_21390) | 82887..83330 | - | 444 | WP_263794345.1 | DUF2384 domain-containing protein | Antitoxin |
| NG826_RS21435 (NG826_21395) | 83717..83941 | + | 225 | WP_013027863.1 | KTSC domain-containing protein | - |
| NG826_RS21440 (NG826_21400) | 84081..84776 | + | 696 | WP_263794346.1 | hypothetical protein | - |
| NG826_RS21445 (NG826_21405) | 84852..85541 | - | 690 | WP_047713812.1 | HTH-type transcriptional regulator RutR | - |
| NG826_RS21450 (NG826_21410) | 85940..87031 | + | 1092 | WP_263794347.1 | pyrimidine utilization protein A | - |
| NG826_RS21455 (NG826_21415) | 87028..87780 | + | 753 | WP_028722713.1 | pyrimidine utilization protein B | - |
| NG826_RS21460 (NG826_21420) | 87806..88192 | + | 387 | WP_013027868.1 | pyrimidine utilization protein C | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | fliC / tssG / tssF / icmF/tssM / vgrG/tssI / clpV/tssH / hcp/tssD / dotU/tssL / vasE/tssK / vipB/tssC / vipA/tssB | 1..286165 | 286165 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 156 a.a. Molecular weight: 17234.72 Da Isoelectric Point: 5.1570
>T249094 WP_047713814.1 NZ_CP099536:c82890-82423 [Pantoea ananatis]
MKLYRMTKTRYLGSAWSGFGAREGGGRWNSVGVSMVYASETASLTMLETLIHLQSASVLDFFTLMSIDVPDRLIEWIDIK
QLPDDWAAPEAPAALRLFGDAWIQSGGSVALRVPSALSPVESNYLLNPEHPEFNAIVRQAVNIPFLFDVRFSRQA
MKLYRMTKTRYLGSAWSGFGAREGGGRWNSVGVSMVYASETASLTMLETLIHLQSASVLDFFTLMSIDVPDRLIEWIDIK
QLPDDWAAPEAPAALRLFGDAWIQSGGSVALRVPSALSPVESNYLLNPEHPEFNAIVRQAVNIPFLFDVRFSRQA
Download Length: 468 bp
Antitoxin
Download Length: 148 a.a. Molecular weight: 16407.75 Da Isoelectric Point: 7.0208
>AT249094 WP_263794345.1 NZ_CP099536:c83330-82887 [Pantoea ananatis]
MKQFTLPVSAAEPDRLWQFAGLSSADGMMLMDQIDDGLDGTVASRIVTWAQISQAELRRMTGIAGSTFTRGVKSRFTAEQ
SERLVRFIRVMDRAVELFEGDKEKARQWLNEPARALGNKKPADLVASETGAYEVLKLITRLEHGVYS
MKQFTLPVSAAEPDRLWQFAGLSSADGMMLMDQIDDGLDGTVASRIVTWAQISQAELRRMTGIAGSTFTRGVKSRFTAEQ
SERLVRFIRVMDRAVELFEGDKEKARQWLNEPARALGNKKPADLVASETGAYEVLKLITRLEHGVYS
Download Length: 444 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|