249088

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 507341..508079 Replicon chromosome
Accession NZ_CP099535
Organism Pantoea ananatis strain JT1-188

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NG826_RS02455 Protein ID WP_144839663.1
Coordinates 507341..507721 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NG826_RS02460 Protein ID WP_144839661.1
Coordinates 507753..508079 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG826_RS02430 (NG826_02430) 503259..505274 + 2016 WP_260411985.1 fimbria/pilus outer membrane usher protein -
NG826_RS02435 (NG826_02435) 505246..505950 + 705 WP_263793792.1 fimbria/pilus periplasmic chaperone -
NG826_RS02440 (NG826_02440) 506270..506407 - 138 Protein_470 IS3 family transposase -
NG826_RS02445 (NG826_02445) 506451..506768 - 318 Protein_471 integrase core domain-containing protein -
NG826_RS02450 (NG826_02450) 507135..507344 - 210 WP_144839665.1 DUF5983 family protein -
NG826_RS02455 (NG826_02455) 507341..507721 - 381 WP_144839663.1 TA system toxin CbtA family protein Toxin
NG826_RS02460 (NG826_02460) 507753..508079 - 327 WP_144839661.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NG826_RS02465 (NG826_02465) 508090..508557 - 468 WP_144839659.1 DNA repair protein RadC -
NG826_RS02470 (NG826_02470) 508572..508991 - 420 WP_248260975.1 antirestriction protein -
NG826_RS02475 (NG826_02475) 509122..509643 - 522 WP_248260976.1 IrmA family protein -
NG826_RS02480 (NG826_02480) 509619..510248 - 630 WP_248260977.1 hypothetical protein -
NG826_RS02485 (NG826_02485) 510254..510955 - 702 WP_039270018.1 WYL domain-containing protein -
NG826_RS02490 (NG826_02490) 511168..512043 - 876 WP_248260978.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 506451..506771 320


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(5-103)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13851.75 Da        Isoelectric Point: 6.0622

>T249088 WP_144839663.1 NZ_CP099535:c507721-507341 [Pantoea ananatis]
MQTLPLPEPRAAEPCPSPVQVWQLLLTHLLDKHYGLTLNDTPFGDDSVIQAHINAGISLCDAVNFIVERYELVRTDHSCF
SLTERSSLIGAIDILRARRATGLIVSSGYSTITRITTGRYQGGEAQ

Download         Length: 381 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11980.49 Da        Isoelectric Point: 6.3159

>AT249088 WP_144839661.1 NZ_CP099535:c508079-507753 [Pantoea ananatis]
MHSEQWGLTCGKTPCFSARLVQEGNRLHFLADRAGFTGEFSNDEALRLDQAFPLIMKQLEQMLSAGELNPRHQQRVTLQH
NGLACEADTLGSHGYVYIAIYPSSTVTG

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References