Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 131422..132074 Replicon chromosome
Accession NZ_CP099535
Organism Pantoea ananatis strain JT1-188

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag NG826_RS00620 Protein ID WP_033778077.1
Coordinates 131676..132074 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag NG826_RS00615 Protein ID WP_028724117.1
Coordinates 131422..131652 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG826_RS00600 (NG826_00600) 127394..128602 + 1209 WP_263793723.1 conjugal transfer protein TraF -
NG826_RS00605 (NG826_00605) 128656..129210 + 555 WP_263775424.1 hypothetical protein -
NG826_RS00610 (NG826_00610) 129676..130834 - 1159 Protein_119 IS30 family transposase -
NG826_RS00615 (NG826_00615) 131422..131652 + 231 WP_028724117.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NG826_RS00620 (NG826_00620) 131676..132074 + 399 WP_033778077.1 type II toxin-antitoxin system VapC family toxin Toxin
NG826_RS00625 (NG826_00625) 132301..133176 - 876 WP_050598417.1 N-acetylmuramoyl-L-alanine amidase -
NG826_RS00630 (NG826_00630) 133206..133487 - 282 WP_028724120.1 LuxR C-terminal-related transcriptional regulator -
NG826_RS00635 (NG826_00635) 133896..134453 + 558 WP_028724121.1 fimbrial protein -
NG826_RS00640 (NG826_00640) 134516..135187 + 672 WP_028724122.1 fimbria/pilus periplasmic chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 130235..181522 51287


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14290.62 Da        Isoelectric Point: 7.2161

>T249087 WP_033778077.1 NZ_CP099535:131676-132074 [Pantoea ananatis]
MLDTCICSFIMREQPEAVLKRLEQAVLRGHRIVVSAITYAEMRFGASGPKASPRHVQLVDAFCARLDAVLPWDRAAVDAT
TEIKVSLRLAGTPIGPNDTAIAGHAITVGAILVTNNVREFARVPGLALEDWV

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8702.83 Da        Isoelectric Point: 4.6158

>AT249087 WP_028724117.1 NZ_CP099535:131422-131652 [Pantoea ananatis]
MRTVSIFKNGNNRAIRLPRDLDFDGVSELEIVREGDSIILRPVRPTWGSFLELEKADPHFMAERGDVVSDEGRFDL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References