249086

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4590231..4590573 Replicon chromosome
Accession NZ_CP099534
Organism Xanthomonas sacchari strain JR3-14

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6N7QE65
Locus tag NG824_RS19725 Protein ID WP_026143575.1
Coordinates 4590231..4590365 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A6N7QPX8
Locus tag NG824_RS19730 Protein ID WP_017908941.1
Coordinates 4590421..4590573 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG824_RS19700 (NG824_19680) 4585895..4586005 - 111 Protein_3875 peptidase -
NG824_RS19705 (NG824_19685) 4586113..4587045 - 933 WP_267093065.1 MBL fold metallo-hydrolase -
NG824_RS19710 (NG824_19690) 4587406..4588698 - 1293 WP_152236650.1 tryptophan--tRNA ligase -
NG824_RS19715 (NG824_19695) 4588855..4589757 + 903 WP_267093066.1 hypothetical protein -
NG824_RS19720 (NG824_19700) 4589829..4590044 - 216 WP_010341025.1 CsbD family protein -
NG824_RS19725 (NG824_19705) 4590231..4590365 - 135 WP_026143575.1 entericidin A/B family lipoprotein Toxin
NG824_RS19730 (NG824_19710) 4590421..4590573 - 153 WP_017908941.1 entericidin A/B family lipoprotein Antitoxin
NG824_RS19735 (NG824_19715) 4590716..4591639 - 924 WP_152181592.1 arginase -
NG824_RS19740 (NG824_19720) 4591884..4592585 + 702 WP_267093067.1 hypothetical protein -
NG824_RS19750 (NG824_19730) 4592779..4593627 - 849 WP_267093068.1 SPOR domain-containing protein -
NG824_RS19755 (NG824_19735) 4593750..4594499 - 750 WP_267093069.1 type III pantothenate kinase -
NG824_RS19760 (NG824_19740) 4594496..4595461 - 966 WP_267094224.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4628.46 Da        Isoelectric Point: 10.2066

>T249086 WP_026143575.1 NZ_CP099534:c4590365-4590231 [Xanthomonas sacchari]
MKRTFAWMLLAMFSVGLLAGCNTVAGAGKDVQKAGEKVQDAAKN

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5181.14 Da        Isoelectric Point: 8.1219

>AT249086 WP_017908941.1 NZ_CP099534:c4590573-4590421 [Xanthomonas sacchari]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDTAKDCSAGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6N7QE65

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7QPX8

References