249084

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4625443..4625785 Replicon chromosome
Accession NZ_CP099533
Organism Xanthomonas sacchari strain LT6-2

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6N7QE65
Locus tag NG827_RS19785 Protein ID WP_026143575.1
Coordinates 4625443..4625577 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A6N7QPX8
Locus tag NG827_RS19790 Protein ID WP_017908941.1
Coordinates 4625633..4625785 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG827_RS19760 (NG827_19740) 4621048..4621158 - 111 Protein_3888 peptidase -
NG827_RS19765 (NG827_19745) 4621266..4622198 - 933 WP_267097371.1 MBL fold metallo-hydrolase -
NG827_RS19770 (NG827_19750) 4622625..4623917 - 1293 WP_267097372.1 tryptophan--tRNA ligase -
NG827_RS19775 (NG827_19755) 4624026..4624970 + 945 WP_267097373.1 hypothetical protein -
NG827_RS19780 (NG827_19760) 4625041..4625256 - 216 WP_010341025.1 CsbD family protein -
NG827_RS19785 (NG827_19765) 4625443..4625577 - 135 WP_026143575.1 entericidin A/B family lipoprotein Toxin
NG827_RS19790 (NG827_19770) 4625633..4625785 - 153 WP_017908941.1 entericidin A/B family lipoprotein Antitoxin
NG827_RS19795 (NG827_19775) 4625928..4626851 - 924 WP_026144365.1 arginase -
NG827_RS19800 (NG827_19780) 4627007..4627150 + 144 WP_267097374.1 hypothetical protein -
NG827_RS19805 (NG827_19785) 4627160..4628119 + 960 WP_267097375.1 hypothetical protein -
NG827_RS19815 (NG827_19795) 4628398..4629246 - 849 WP_267097376.1 SPOR domain-containing protein -
NG827_RS19820 (NG827_19800) 4629378..4630121 - 744 WP_267097377.1 type III pantothenate kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4628.46 Da        Isoelectric Point: 10.2066

>T249084 WP_026143575.1 NZ_CP099533:c4625577-4625443 [Xanthomonas sacchari]
MKRTFAWMLLAMFSVGLLAGCNTVAGAGKDVQKAGEKVQDAAKN

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5181.14 Da        Isoelectric Point: 8.1219

>AT249084 WP_017908941.1 NZ_CP099533:c4625785-4625633 [Xanthomonas sacchari]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDTAKDCSAGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6N7QE65


Antitoxin

Source ID Structure
AlphaFold DB A0A6N7QPX8

References