249083

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4537445..4537787 Replicon chromosome
Accession NZ_CP099532
Organism Xanthomonas sacchari strain LT6-16-1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6N7QE65
Locus tag NG829_RS19715 Protein ID WP_026143575.1
Coordinates 4537445..4537579 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A6N7QPX8
Locus tag NG829_RS19720 Protein ID WP_017908941.1
Coordinates 4537635..4537787 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG829_RS19690 (NG829_19690) 4533044..4533154 - 111 Protein_3874 peptidase -
NG829_RS19695 (NG829_19695) 4533262..4534194 - 933 WP_267121536.1 MBL fold metallo-hydrolase -
NG829_RS19700 (NG829_19700) 4534621..4535913 - 1293 WP_267121537.1 tryptophan--tRNA ligase -
NG829_RS19705 (NG829_19705) 4536070..4536972 + 903 WP_152236651.1 hypothetical protein -
NG829_RS19710 (NG829_19710) 4537043..4537258 - 216 WP_043093613.1 CsbD family protein -
NG829_RS19715 (NG829_19715) 4537445..4537579 - 135 WP_026143575.1 entericidin A/B family lipoprotein Toxin
NG829_RS19720 (NG829_19720) 4537635..4537787 - 153 WP_017908941.1 entericidin A/B family lipoprotein Antitoxin
NG829_RS19725 (NG829_19725) 4537930..4538853 - 924 WP_026144365.1 arginase -
NG829_RS19730 (NG829_19730) 4539269..4539601 + 333 WP_267122583.1 hypothetical protein -
NG829_RS19740 (NG829_19740) 4540013..4540861 - 849 WP_267121538.1 SPOR domain-containing protein -
NG829_RS19745 (NG829_19745) 4540956..4541699 - 744 WP_267121539.1 type III pantothenate kinase -
NG829_RS19750 (NG829_19750) 4541696..4542661 - 966 WP_043095325.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4628.46 Da        Isoelectric Point: 10.2066

>T249083 WP_026143575.1 NZ_CP099532:c4537579-4537445 [Xanthomonas sacchari]
MKRTFAWMLLAMFSVGLLAGCNTVAGAGKDVQKAGEKVQDAAKN

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5181.14 Da        Isoelectric Point: 8.1219

>AT249083 WP_017908941.1 NZ_CP099532:c4537787-4537635 [Xanthomonas sacchari]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDTAKDCSAGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6N7QE65

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7QPX8

References