Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4705834..4706176 Replicon chromosome
Accession NZ_CP099530
Organism Xanthomonas sacchari strain YT9-19-2

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6N7QE65
Locus tag NG828_RS20305 Protein ID WP_026143575.1
Coordinates 4705834..4705968 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A6N7QPX8
Locus tag NG828_RS20310 Protein ID WP_017908941.1
Coordinates 4706024..4706176 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG828_RS20280 (NG828_20245) 4701507..4701617 - 111 Protein_3992 peptidase -
NG828_RS20285 (NG828_20250) 4701725..4702657 - 933 WP_267082227.1 MBL fold metallo-hydrolase -
NG828_RS20290 (NG828_20255) 4703017..4704309 - 1293 WP_267082228.1 tryptophan--tRNA ligase -
NG828_RS20295 (NG828_20260) 4704418..4705362 + 945 WP_267082229.1 hypothetical protein -
NG828_RS20300 (NG828_20265) 4705433..4705648 - 216 WP_010341025.1 CsbD family protein -
NG828_RS20305 (NG828_20270) 4705834..4705968 - 135 WP_026143575.1 entericidin A/B family lipoprotein Toxin
NG828_RS20310 (NG828_20275) 4706024..4706176 - 153 WP_017908941.1 entericidin A/B family lipoprotein Antitoxin
NG828_RS20315 (NG828_20280) 4706319..4707242 - 924 WP_267082230.1 arginase -
NG828_RS20320 (NG828_20285) 4707405..4710581 + 3177 WP_267082231.1 filamentous hemagglutinin N-terminal domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4628.46 Da        Isoelectric Point: 10.2066

>T249079 WP_026143575.1 NZ_CP099530:c4705968-4705834 [Xanthomonas sacchari]
MKRTFAWMLLAMFSVGLLAGCNTVAGAGKDVQKAGEKVQDAAKN

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5181.14 Da        Isoelectric Point: 8.1219

>AT249079 WP_017908941.1 NZ_CP099530:c4706176-4706024 [Xanthomonas sacchari]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDTAKDCSAGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6N7QE65


Antitoxin

Source ID Structure
AlphaFold DB A0A6N7QPX8

References