Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4672370..4672712 Replicon chromosome
Accession NZ_CP099529
Organism Xanthomonas sacchari strain HR1-32

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6N7QE65
Locus tag NG831_RS20460 Protein ID WP_026143575.1
Coordinates 4672370..4672504 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A6N7QPX8
Locus tag NG831_RS20465 Protein ID WP_017908941.1
Coordinates 4672560..4672712 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG831_RS20435 (NG831_20390) 4668041..4668152 - 112 Protein_4024 peptidase -
NG831_RS20440 (NG831_20395) 4668260..4669193 - 934 Protein_4025 MBL fold metallo-hydrolase -
NG831_RS20445 (NG831_20400) 4669551..4670843 - 1293 WP_267110692.1 tryptophan--tRNA ligase -
NG831_RS20450 (NG831_20405) 4671000..4671896 + 897 WP_267110693.1 hypothetical protein -
NG831_RS20455 (NG831_20410) 4671968..4672183 - 216 WP_010341025.1 CsbD family protein -
NG831_RS20460 (NG831_20415) 4672370..4672504 - 135 WP_026143575.1 entericidin A/B family lipoprotein Toxin
NG831_RS20465 (NG831_20420) 4672560..4672712 - 153 WP_017908941.1 entericidin A/B family lipoprotein Antitoxin
NG831_RS20470 (NG831_20425) 4672855..4673778 - 924 WP_267082230.1 arginase -
NG831_RS20475 (NG831_20430) 4673940..4677116 + 3177 WP_267112973.1 filamentous hemagglutinin N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 4666702..4667646 944


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4628.46 Da        Isoelectric Point: 10.2066

>T249077 WP_026143575.1 NZ_CP099529:c4672504-4672370 [Xanthomonas sacchari]
MKRTFAWMLLAMFSVGLLAGCNTVAGAGKDVQKAGEKVQDAAKN

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5181.14 Da        Isoelectric Point: 8.1219

>AT249077 WP_017908941.1 NZ_CP099529:c4672712-4672560 [Xanthomonas sacchari]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDTAKDCSAGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6N7QE65

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7QPX8

References