Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1972653..1972798 Replicon chromosome
Accession NZ_CP099522
Organism Klebsiella pneumoniae strain SZS128

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1972689..1972791 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1972653..1972798 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG894_RS09685 (NG894_09670) 1967783..1969843 + 2061 WP_004151449.1 oligopeptidase B -
NG894_RS09690 (NG894_09675) 1969847..1970506 - 660 WP_002911407.1 exodeoxyribonuclease X -
NG894_RS09695 (NG894_09680) 1970585..1970815 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NG894_RS09700 (NG894_09685) 1970928..1971302 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NG894_RS09705 (NG894_09690) 1971306..1972175 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NG894_RS09710 (NG894_09695) 1972192..1972530 + 339 WP_002911404.1 YebY family protein -
- 1972653..1972798 - 146 - - Antitoxin
- 1972689..1972791 + 103 - - Toxin
NG894_RS09715 (NG894_09700) 1973166..1973309 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NG894_RS09720 (NG894_09705) 1973414..1974382 - 969 WP_004151446.1 VirK/YbjX family protein -
NG894_RS09725 (NG894_09710) 1974539..1975192 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NG894_RS09730 (NG894_09715) 1975189..1975380 - 192 WP_002911395.1 YebW family protein -
NG894_RS09735 (NG894_09720) 1975478..1975717 - 240 WP_002911393.1 YebV family protein -
NG894_RS09740 (NG894_09725) 1975833..1977266 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T249060 NZ_CP099522:1972689-1972791 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT249060 NZ_CP099522:c1972798-1972653 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References