Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 3086683..3087356 Replicon chromosome
Accession NZ_CP099511
Organism Lelliottia amnigena strain P13

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFJ01_RS14810 Protein ID WP_252686304.1
Coordinates 3086683..3087003 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFJ01_RS14815 Protein ID WP_252686306.1
Coordinates 3087036..3087356 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ01_RS14790 (NFJ01_14790) 3081796..3082497 + 702 WP_252686296.1 oligogalacturonate-specific porin KdgM family protein -
NFJ01_RS14795 (NFJ01_14795) 3082568..3084277 + 1710 WP_252686298.1 pectate lyase -
NFJ01_RS14800 (NFJ01_14800) 3084663..3085532 + 870 WP_252686300.1 HNH endonuclease -
NFJ01_RS14805 (NFJ01_14805) 3085733..3086569 - 837 WP_252686302.1 DUF4942 domain-containing protein -
NFJ01_RS14810 (NFJ01_14810) 3086683..3087003 - 321 WP_252686304.1 TA system toxin CbtA family protein Toxin
NFJ01_RS14815 (NFJ01_14815) 3087036..3087356 - 321 WP_252686306.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ01_RS14820 (NFJ01_14820) 3087353..3087823 - 471 WP_252686308.1 DNA repair protein RadC -
NFJ01_RS14825 (NFJ01_14825) 3087889..3088707 - 819 WP_252686310.1 DUF932 domain-containing protein -
NFJ01_RS14830 (NFJ01_14830) 3088796..3089272 - 477 WP_252686312.1 hypothetical protein -
NFJ01_RS14835 (NFJ01_14835) 3089304..3089477 - 174 WP_196230737.1 hypothetical protein -
NFJ01_RS14840 (NFJ01_14840) 3089494..3090360 - 867 WP_252686314.1 hypothetical protein -
NFJ01_RS14845 (NFJ01_14845) 3090500..3090934 - 435 WP_252686316.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3086683..3114093 27410


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(6-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12163.99 Da        Isoelectric Point: 6.0641

>T249041 WP_252686304.1 NZ_CP099511:c3087003-3086683 [Lelliottia amnigena]
MQISTVPATVPVSPRLSPVQVWQQLLSYLLEHHYGLMLNDTPFHYDAAILEHIEARITLADAVNFLVDRYELVRIDRKGF
SWQEQEPFLTAADILRAKRATGLMNT

Download         Length: 321 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11922.66 Da        Isoelectric Point: 6.6285

>AT249041 WP_252686306.1 NZ_CP099511:c3087356-3087036 [Lelliottia amnigena]
MKSTLHEWGLQPDISPRFGARLVQEGNRLHYLADRAAFAGSFTPEQLQKLEQVFPLLLEHLENMLCSGELNPRWQHQVKI
HLAGLTCVADTGASCGYVYISIYPAQ

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References