248961

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 1132265..1132741 Replicon chromosome
Accession NZ_CP099495
Organism Staphylococcus aureus strain JL28

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag LPT16_RS05610 Protein ID WP_000052076.1
Coordinates 1132553..1132741 (+) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag LPT16_RS05605 Protein ID WP_001059690.1
Coordinates 1132265..1132525 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPT16_RS05570 (1127663) 1127663..1128379 - 717 WP_000150026.1 type I 3-dehydroquinate dehydratase -
LPT16_RS05575 (1128527) 1128527..1128949 + 423 WP_000974452.1 organic hydroperoxide resistance protein -
LPT16_RS05580 (1129348) 1129348..1129842 + 495 WP_000569881.1 GNAT family N-acetyltransferase -
LPT16_RS05585 (1129991) 1129991..1130608 + 618 WP_000255562.1 LysE/ArgO family amino acid transporter -
LPT16_RS05590 (1130681) 1130681..1131262 - 582 WP_229360221.1 histidine phosphatase family protein -
LPT16_RS05595 (1131487) 1131487..1131723 + 237 WP_000368687.1 hypothetical protein -
LPT16_RS05600 (1131720) 1131720..1131923 - 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
LPT16_RS05605 (1132265) 1132265..1132525 + 261 WP_001059690.1 hypothetical protein Antitoxin
LPT16_RS05610 (1132553) 1132553..1132741 + 189 WP_000052076.1 hypothetical protein Toxin
LPT16_RS05615 (1132929) 1132929..1133498 + 570 WP_001106655.1 lipoprotein N-acylation protein LnsA -
LPT16_RS05620 (1133586) 1133586..1133870 + 285 WP_001004403.1 hypothetical protein -
LPT16_RS05625 (1133931) 1133931..1134149 + 219 WP_000005881.1 hypothetical protein -
LPT16_RS05630 (1134646) 1134646..1134846 - 201 WP_001059082.1 cold-shock protein -
LPT16_RS05635 (1135203) 1135203..1135889 - 687 WP_001574556.1 thermonuclease family protein -
LPT16_RS05640 (1136230) 1136230..1136712 - 483 WP_000824489.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T248961 WP_000052076.1 NZ_CP099495:1132553-1132741 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT248961 WP_001059690.1 NZ_CP099495:1132265-1132525 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References