Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3224040..3224665 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF557_RS14780 Protein ID WP_252620353.1
Coordinates 3224040..3224450 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF557_RS17635 Protein ID WP_280923965.1
Coordinates 3224441..3224665 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS14745 (NF557_14745) 3219392..3219874 + 483 WP_252620343.1 AAA family ATPase -
NF557_RS14750 (NF557_14750) 3220187..3220696 - 510 WP_252620345.1 hypothetical protein -
NF557_RS14755 (NF557_14755) 3221479..3221703 + 225 WP_252620347.1 addiction module protein -
NF557_RS14760 (NF557_14760) 3221700..3221897 + 198 WP_252620348.1 hypothetical protein -
NF557_RS14770 (NF557_14770) 3222754..3223377 + 624 WP_252620350.1 YceI family protein -
NF557_RS14775 (NF557_14775) 3223663..3223863 - 201 WP_252620351.1 hypothetical protein -
NF557_RS14780 (NF557_14780) 3224040..3224450 - 411 WP_252620353.1 PIN domain nuclease Toxin
NF557_RS17635 3224441..3224665 - 225 WP_280923965.1 antitoxin Antitoxin
NF557_RS14790 (NF557_14790) 3224792..3225172 + 381 WP_252620358.1 Rid family hydrolase -
NF557_RS14795 (NF557_14795) 3225525..3226049 + 525 WP_252620359.1 CarD family transcriptional regulator -
NF557_RS14800 (NF557_14800) 3226137..3227027 + 891 WP_252620361.1 alpha/beta hydrolase -
NF557_RS14805 (NF557_14805) 3227132..3227536 + 405 WP_252620363.1 hypothetical protein -
NF557_RS14810 (NF557_14810) 3227559..3228629 + 1071 WP_252620364.1 PHB depolymerase family esterase -
NF557_RS14815 (NF557_14815) 3228685..3229290 + 606 WP_252620366.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(11-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14888.16 Da        Isoelectric Point: 5.6660

>T248953 WP_252620353.1 NZ_CP099490:c3224450-3224040 [Ornithinimicrobium cryptoxanthini]
VAVSEWLIDKLALVRLADSPDAQEWAGRIHRGLVRVTNVTRLEIGYSARNEDDARSLFAALPVAAMPVEYLTPTIEDRAL
QVQLLLAGRGLRRAPSIPDLFIAAAAELAGLSVLHLDKEFDLIASITGQRAERLHV

Download         Length: 411 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8114.27 Da        Isoelectric Point: 4.7085

>AT248953 WP_280923965.1 NZ_CP099490:c3224665-3224441 [Ornithinimicrobium cryptoxanthini]
MMADVLIRDVPEAVLARVDARAARLGLSRVEYIRRRLAADAASEGSPVSVGDLRAFANRFADLADPEVMESVWQ

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References