Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2947791..2948401 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF557_RS13570 Protein ID WP_252620058.1
Coordinates 2947997..2948401 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF557_RS13565 Protein ID WP_252620057.1
Coordinates 2947791..2948000 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS13555 (NF557_13555) 2943343..2944296 + 954 WP_252620055.1 histone-like nucleoid-structuring protein Lsr2 -
NF557_RS13560 (NF557_13560) 2944381..2947764 + 3384 WP_252620056.1 DEAD/DEAH box helicase -
NF557_RS13565 (NF557_13565) 2947791..2948000 + 210 WP_252620057.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NF557_RS13570 (NF557_13570) 2947997..2948401 + 405 WP_252620058.1 PIN domain nuclease Toxin
NF557_RS13575 (NF557_13575) 2948413..2949594 - 1182 WP_252620059.1 acyl-CoA dehydrogenase family protein -
NF557_RS13580 (NF557_13580) 2949685..2950857 - 1173 WP_252620060.1 N(5)-(carboxyethyl)ornithine synthase -
NF557_RS17615 2950841..2950975 - 135 WP_256842133.1 hypothetical protein -
NF557_RS13585 (NF557_13585) 2951049..2951819 - 771 WP_252620061.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14924.23 Da        Isoelectric Point: 6.7089

>T248951 WP_252620058.1 NZ_CP099490:2947997-2948401 [Ornithinimicrobium cryptoxanthini]
VIVDTSVWIEFLRPGRSSAGDHLESLIRRRERLVVPETVLMELLSSTTDETAAARQRRMLESFEIAPLEPVVDSLAAARL
QRQCRRSGEAVRNLGDCLIAAVALRLAIPVLHRDRDFEALRTHCGVETVSLLPA

Download         Length: 405 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7821.73 Da        Isoelectric Point: 3.9956

>AT248951 WP_252620057.1 NZ_CP099490:2947791-2948000 [Ornithinimicrobium cryptoxanthini]
VTRTNIDLDDELVAAVMARYRLESKRSAVDFALRQLVREPLSLEEILAMRGSGIEVDNEEIEGDWTADE

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References