Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2857857..2858425 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF557_RS13140 Protein ID WP_252619975.1
Coordinates 2857857..2858231 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF557_RS13145 Protein ID WP_252619976.1
Coordinates 2858228..2858425 (-) Length 66 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS13130 (NF557_13130) 2855481..2857211 + 1731 WP_252619973.1 AMP-binding protein -
NF557_RS13135 (NF557_13135) 2857239..2857814 - 576 WP_252619974.1 peroxidase-related enzyme -
NF557_RS13140 (NF557_13140) 2857857..2858231 - 375 WP_252619975.1 type II toxin-antitoxin system VapC family toxin Toxin
NF557_RS13145 (NF557_13145) 2858228..2858425 - 198 WP_252619976.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NF557_RS13150 (NF557_13150) 2858508..2860118 - 1611 WP_252619977.1 molybdopterin-dependent oxidoreductase -
NF557_RS13155 (NF557_13155) 2860209..2860637 + 429 WP_252619978.1 protease inhibitor I42 family protein -
NF557_RS13160 (NF557_13160) 2860689..2861987 + 1299 WP_252619979.1 C1 family peptidase -
NF557_RS13165 (NF557_13165) 2862016..2862783 - 768 WP_252624185.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(1-42)


Sequences


Toxin        


Download         Length: 125 a.a.        Molecular weight: 13371.50 Da        Isoelectric Point: 6.4797

>T248949 WP_252619975.1 NZ_CP099490:c2858231-2857857 [Ornithinimicrobium cryptoxanthini]
VILVDTSIWIDHLHTSQPDLVRLLDQDAVGCHPAVVEELALGSIAQRDVVLALLESLHQFPVLGHAELLTLVSGRRLWGR
GLSAVDGHLLGAVALVSGARLWTRDRRLMAACRDAGVACLGERT

Download         Length: 375 bp


Antitoxin


Download         Length: 66 a.a.        Molecular weight: 6938.84 Da        Isoelectric Point: 11.0634

>AT248949 WP_252619976.1 NZ_CP099490:c2858425-2858228 [Ornithinimicrobium cryptoxanthini]
MRTTVNIDDELFARASELTGVSERAALLRDGLRTLIRVESAKRLAALGGSDPSATAAPRRREGTA

Download         Length: 198 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References