Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2750482..2751270 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NF557_RS12680 Protein ID WP_252619891.1
Coordinates 2750767..2751270 (+) Length 168 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag NF557_RS12675 Protein ID WP_252619889.1
Coordinates 2750482..2750766 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS12645 (NF557_12645) 2746026..2746901 + 876 WP_252619877.1 mechanosensitive ion channel family protein -
NF557_RS12650 (NF557_12650) 2746938..2747549 + 612 WP_252619879.1 winged helix-turn-helix domain-containing protein -
NF557_RS12655 (NF557_12655) 2747546..2748787 + 1242 WP_252619881.1 MFS transporter -
NF557_RS12660 (NF557_12660) 2748860..2749216 + 357 WP_252619883.1 YciI family protein -
NF557_RS12665 (NF557_12665) 2749309..2749704 + 396 WP_252619885.1 globin -
NF557_RS12670 (NF557_12670) 2749752..2750321 + 570 WP_252619887.1 GNAT family N-acetyltransferase -
NF557_RS12675 (NF557_12675) 2750482..2750766 + 285 WP_252619889.1 DUF1778 domain-containing protein Antitoxin
NF557_RS12680 (NF557_12680) 2750767..2751270 + 504 WP_252619891.1 GNAT family N-acetyltransferase Toxin
NF557_RS12685 (NF557_12685) 2751356..2752531 + 1176 WP_252619893.1 DUF2786 domain-containing protein -
NF557_RS12690 (NF557_12690) 2752528..2753286 - 759 WP_252619895.1 TetR/AcrR family transcriptional regulator -
NF557_RS12695 (NF557_12695) 2753346..2754314 + 969 WP_252619896.1 ATP-binding cassette domain-containing protein -
NF557_RS12700 (NF557_12700) 2754311..2755099 + 789 WP_252619897.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-145)

Antitoxin

Vibrio phage ICP1, Orf50

(11-86)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 17856.51 Da        Isoelectric Point: 9.5214

>T248948 WP_252619891.1 NZ_CP099490:2750767-2751270 [Ornithinimicrobium cryptoxanthini]
VTPLQPRPIRARDDCTAFESGEPSLDGYLRDRALSNHLADLARCYVCTEVASNRVLGYYTLSAVAVSRSALPGRARRNAP
DPVPAVLLGRLAVDRMAQGSGLGRLLVRDAIVSTLAAADRIGVRALLVHALHERAASFYGGLGFATSPTDPLHLYVLLAD
VRRSLPG

Download         Length: 504 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10330.62 Da        Isoelectric Point: 4.6182

>AT248948 WP_252619889.1 NZ_CP099490:2750482-2750766 [Ornithinimicrobium cryptoxanthini]
MSETPGRKAARLAMRLTPEQDALIREAAATTGQSLTEFVTTAAVARAQDSLADRRMFRLSDEAWAEFSALLDRPGQRVPS
LAALLDEQAPWDKD

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References