Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2286611..2287152 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NF557_RS10515 Protein ID WP_252619213.1
Coordinates 2286850..2287152 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NF557_RS10510 Protein ID WP_269762039.1
Coordinates 2286611..2286850 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS10495 (NF557_10495) 2283860..2284555 - 696 WP_252619210.1 response regulator transcription factor -
NF557_RS10500 (NF557_10500) 2284655..2285887 - 1233 WP_252619211.1 tRNA dihydrouridine synthase DusB -
NF557_RS10505 (NF557_10505) 2285930..2286478 - 549 WP_252619212.1 type 1 glutamine amidotransferase domain-containing protein -
NF557_RS10510 (NF557_10510) 2286611..2286850 + 240 WP_269762039.1 ribbon-helix-helix domain-containing protein Antitoxin
NF557_RS10515 (NF557_10515) 2286850..2287152 + 303 WP_252619213.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NF557_RS10520 (NF557_10520) 2287156..2287716 - 561 WP_252619214.1 (d)CMP kinase -
NF557_RS10525 (NF557_10525) 2287713..2288177 - 465 WP_252619215.1 NUDIX domain-containing protein -
NF557_RS10530 (NF557_10530) 2288297..2288965 - 669 WP_252619216.1 FMN reductase -
NF557_RS10535 (NF557_10535) 2288965..2290095 - 1131 WP_252619217.1 LLM class flavin-dependent oxidoreductase -
NF557_RS10540 (NF557_10540) 2290276..2291514 - 1239 WP_252619218.1 hypothetical protein -
NF557_RS10545 (NF557_10545) 2291511..2292050 - 540 WP_252619219.1 SigE family RNA polymerase sigma factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-92)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-43)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10824.45 Da        Isoelectric Point: 6.4632

>T248947 WP_252619213.1 NZ_CP099490:2286850-2287152 [Ornithinimicrobium cryptoxanthini]
MRPIHAVRLDKVRPALVLTRPEVRLARTSVTVAAITSTRRGLSVELPVGPANGLGRESVVNLDTIYTIAVDDLGPQLGTL
REDQEPDLAAAVFHAFGLDW

Download         Length: 303 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8980.02 Da        Isoelectric Point: 4.8146

>AT248947 WP_269762039.1 NZ_CP099490:2286611-2286850 [Ornithinimicrobium cryptoxanthini]
MSTQVSLRLSDALVARIDELVRSGAARSRAEVVESALERELRRRLYEQDAEIYRSGEPDPDLDALNTWMQSRRSYPGLG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References