Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1905183..1905747 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NF557_RS08800 Protein ID WP_252618828.1
Coordinates 1905400..1905747 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NF557_RS08795 Protein ID WP_252618827.1
Coordinates 1905183..1905413 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS08770 (NF557_08770) 1900619..1901344 - 726 WP_252618822.1 response regulator transcription factor -
NF557_RS08775 (NF557_08775) 1901341..1901781 - 441 WP_252618823.1 ATP-binding protein -
NF557_RS08780 (NF557_08780) 1901699..1903294 - 1596 WP_252618824.1 hypothetical protein -
NF557_RS08785 (NF557_08785) 1903363..1904088 - 726 WP_252618825.1 hypothetical protein -
NF557_RS08790 (NF557_08790) 1904265..1905173 + 909 WP_252618826.1 alpha/beta fold hydrolase -
NF557_RS08795 (NF557_08795) 1905183..1905413 + 231 WP_252618827.1 ribbon-helix-helix domain-containing protein Antitoxin
NF557_RS08800 (NF557_08800) 1905400..1905747 + 348 WP_252618828.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NF557_RS08805 (NF557_08805) 1906108..1907328 + 1221 WP_252618829.1 hypothetical protein -
NF557_RS08810 (NF557_08810) 1908010..1908531 + 522 WP_252618830.1 hypothetical protein -
NF557_RS08815 (NF557_08815) 1908605..1908868 - 264 WP_252618831.1 type II toxin-antitoxin system RelE/ParE family toxin -
NF557_RS08820 (NF557_08820) 1908865..1909125 - 261 WP_252618832.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
NF557_RS08825 (NF557_08825) 1909309..1909479 - 171 WP_252624332.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-38)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12417.41 Da        Isoelectric Point: 8.9932

>T248946 WP_252618828.1 NZ_CP099490:1905400-1905747 [Ornithinimicrobium cryptoxanthini]
MLRGEILLVDLDPVRGSEANKRRPAVLVSNDQANTMAQRLGRGVVTVAPVTSNAERVFPFQVLLPADETGLRMDSKVQAE
QVRSVAVERVGPALGRVPPGLMAAVDEALRLHLQL

Download         Length: 348 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8208.94 Da        Isoelectric Point: 3.9015

>AT248946 WP_252618827.1 NZ_CP099490:1905183-1905413 [Ornithinimicrobium cryptoxanthini]
MKVSVSLSEEDLAALDRYVQQAGLESRSAAVQQAIRRLQDPQLEADYAAAWQEWAIAGDEDAWAAASSDGLTDAAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References