Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 258626..259286 Replicon chromosome
Accession NZ_CP099490
Organism Ornithinimicrobium cryptoxanthini strain JY.X270

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF557_RS01225 Protein ID WP_252621285.1
Coordinates 258846..259286 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF557_RS01220 Protein ID WP_252621284.1
Coordinates 258626..258853 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF557_RS01200 (NF557_01200) 255038..255265 - 228 WP_252621281.1 hypothetical protein -
NF557_RS01205 (NF557_01205) 255265..256440 - 1176 WP_252621282.1 glycosyltransferase -
NF557_RS01210 (NF557_01210) 256445..258277 - 1833 WP_252621283.1 phosphoenolpyruvate carboxykinase (GTP) -
NF557_RS01220 (NF557_01220) 258626..258853 + 228 WP_252621284.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NF557_RS01225 (NF557_01225) 258846..259286 + 441 WP_252621285.1 hypothetical protein Toxin
NF557_RS01230 (NF557_01230) 259323..259910 + 588 WP_252621286.1 hypothetical protein -
NF557_RS01235 (NF557_01235) 259952..260824 + 873 WP_252621287.1 nucleotidyltransferase family protein -
NF557_RS01240 (NF557_01240) 260821..261114 + 294 WP_252621288.1 PqqD family protein -
NF557_RS01245 (NF557_01245) 261194..262732 + 1539 WP_252621289.1 polysaccharide biosynthesis tyrosine autokinase -
NF557_RS01250 (NF557_01250) 262829..263899 + 1071 WP_252621290.1 O-antigen ligase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(8-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 15790.06 Da        Isoelectric Point: 6.7230

>T248945 WP_252621285.1 NZ_CP099490:258846-259286 [Ornithinimicrobium cryptoxanthini]
MTEPPVTLFDVNALVAVALTTHQHHHAAHRHLRALDGTWATASLTEAGLFRLLLNPLVTGSQRLAADVGAVLQGMRGDPR
WTFLEDATSLADPIVDTTVLMGHRQVTDVHLVNLAARHGGVLATFDAGIRSWLAPEDRHHIVVIPA

Download         Length: 441 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8004.04 Da        Isoelectric Point: 4.4865

>AT248945 WP_252621284.1 NZ_CP099490:258626-258853 [Ornithinimicrobium cryptoxanthini]
MRTTLEIDDQVMAAARSLARSRGTSVGAAVSELARRGLMQSAGARVDAHYSPFPVMVGDEGVLVTDELIAELRDD

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References