Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 4417441..4418057 Replicon chromosome
Accession NZ_CP099489
Organism Ornithinimicrobium sp. HY1793

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF556_RS20315 Protein ID WP_252593020.1
Coordinates 4417668..4418057 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF556_RS20310 Protein ID WP_252593018.1
Coordinates 4417441..4417671 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF556_RS21470 4413509..4414006 - 498 WP_289781770.1 MarR family transcriptional regulator -
NF556_RS20305 (NF556_20305) 4414131..4417370 + 3240 WP_252593016.1 efflux RND transporter permease subunit -
NF556_RS20310 (NF556_20310) 4417441..4417671 + 231 WP_252593018.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF556_RS20315 (NF556_20315) 4417668..4418057 + 390 WP_252593020.1 type II toxin-antitoxin system VapC family toxin Toxin
NF556_RS20320 (NF556_20320) 4418114..4419508 - 1395 WP_252593021.1 glucose-6-phosphate dehydrogenase -
NF556_RS20325 (NF556_20325) 4419605..4421614 - 2010 WP_252593023.1 AarF/UbiB family protein -
NF556_RS20330 (NF556_20330) 4421644..4422249 - 606 WP_252593025.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-42)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14148.14 Da        Isoelectric Point: 6.8800

>T248942 WP_252593020.1 NZ_CP099489:4417668-4418057 [Ornithinimicrobium sp. HY1793]
MTYLLDTHAVLWALTDPARLGPAARQTITARSTRLAVSAATAWEISTKQRIGKLPQADALVGGYSRHLDRLGAIRLPIDE
EHALLAGRLDWSHRDPFDRVFAAQAMLESLTLVTNDSAFAELNGVATLW

Download         Length: 390 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8371.38 Da        Isoelectric Point: 4.0533

>AT248942 WP_252593018.1 NZ_CP099489:4417441-4417671 [Ornithinimicrobium sp. HY1793]
METVKVQYAKTHLSALLAAVERGEEIVIARGDRPVARLSPIDGQDDRELGFVAYSVPDEFFDPLPEEELAVWEGAG

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References