248941

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3795458..3796086 Replicon chromosome
Accession NZ_CP099489
Organism Ornithinimicrobium sp. HY1793

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF556_RS17645 Protein ID WP_256829372.1
Coordinates 3795458..3795877 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF556_RS17650 Protein ID WP_252592455.1
Coordinates 3795868..3796086 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF556_RS17620 (NF556_17620) 3791468..3792394 + 927 WP_252595851.1 LysR family transcriptional regulator -
NF556_RS17625 (NF556_17625) 3792358..3793761 - 1404 WP_252592446.1 glutamate mutase L -
NF556_RS17630 (NF556_17630) 3793743..3794033 - 291 WP_252592447.1 hypothetical protein -
NF556_RS17635 (NF556_17635) 3794187..3794876 + 690 WP_252592449.1 peptide-methionine (S)-S-oxide reductase MsrA -
NF556_RS17640 (NF556_17640) 3794916..3795419 + 504 WP_252592451.1 ATP-binding protein -
NF556_RS17645 (NF556_17645) 3795458..3795877 - 420 WP_256829372.1 PIN domain nuclease Toxin
NF556_RS17650 (NF556_17650) 3795868..3796086 - 219 WP_252592455.1 ribbon-helix-helix protein, CopG family Antitoxin
NF556_RS17655 (NF556_17655) 3796232..3798796 - 2565 WP_252595852.1 ATP-dependent helicase HrpB -
NF556_RS17660 (NF556_17660) 3798814..3799443 - 630 WP_252592456.1 class I SAM-dependent methyltransferase -
NF556_RS17665 (NF556_17665) 3799468..3800427 - 960 WP_252592457.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-125)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-38)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14990.16 Da        Isoelectric Point: 5.5672

>T248941 WP_256829372.1 NZ_CP099489:c3795877-3795458 [Ornithinimicrobium sp. HY1793]
VVLTQPWLIDTSAFARLSTSPDAVVWMERIDRGLVRAATVTLLELGYSARSGADWTNGFQQPPLSHVPVENLTPAMEARA
LVVQGLLAERGHHRAAKVPDLIVAATAETAGLTVLHCDKDFDLIADVTGQPVERLRVSA

Download         Length: 420 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8094.98 Da        Isoelectric Point: 5.0924

>AT248941 WP_252592455.1 NZ_CP099489:c3796086-3795868 [Ornithinimicrobium sp. HY1793]
MTDVLIRNLDDETIRRVDADAARLGLSRNEYLRRAVARLGGAARATTREDLDRFADRFADLSDETVRGAAWS

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References