248940

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 3587181..3587791 Replicon chromosome
Accession NZ_CP099489
Organism Ornithinimicrobium sp. HY1793

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF556_RS16670 Protein ID WP_252592149.1
Coordinates 3587181..3587585 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF556_RS16675 Protein ID WP_252592151.1
Coordinates 3587582..3587791 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF556_RS16645 (NF556_16645) 3582206..3582865 + 660 WP_252592146.1 helix-turn-helix domain-containing protein -
NF556_RS16650 (NF556_16650) 3582906..3583844 - 939 WP_252592148.1 LuxR C-terminal-related transcriptional regulator -
NF556_RS21435 3584051..3587077 + 3027 WP_289781758.1 S8 family peptidase -
NF556_RS16670 (NF556_16670) 3587181..3587585 - 405 WP_252592149.1 PIN domain nuclease Toxin
NF556_RS16675 (NF556_16675) 3587582..3587791 - 210 WP_252592151.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NF556_RS16680 (NF556_16680) 3587981..3588814 - 834 WP_252592153.1 fumarylacetoacetate hydrolase family protein -
NF556_RS16685 (NF556_16685) 3588963..3590987 + 2025 WP_252592155.1 acetoacetate--CoA ligase -
NF556_RS16690 (NF556_16690) 3591044..3592243 + 1200 WP_252592156.1 Fic family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-41)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14860.24 Da        Isoelectric Point: 6.4641

>T248940 WP_252592149.1 NZ_CP099489:c3587585-3587181 [Ornithinimicrobium sp. HY1793]
VIVDTSAWIEFLRPGPSGAGDQLESLIRKQERLVIPEVVLMELLSGTTDEALAARRRRLIESFELTPTEPIVDSLAAASL
QRMCRRGGESVRNLGDCLIASVALRLDLPVMHRDRDFEVLRRHCGIRTVSLIGA

Download         Length: 405 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7700.67 Da        Isoelectric Point: 4.1546

>AT248940 WP_252592151.1 NZ_CP099489:c3587791-3587582 [Ornithinimicrobium sp. HY1793]
MARTNIDIDEDLVAAVMARFRLGSKRAAVDFALQQLIREPMTTEEVLAMRGSGFEVDNDEIEGDWAASR

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References