248938

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 451539..452209 Replicon chromosome
Accession NZ_CP099489
Organism Ornithinimicrobium sp. HY1793

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF556_RS02050 Protein ID WP_252593847.1
Coordinates 451811..452209 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF556_RS02045 Protein ID WP_252593846.1
Coordinates 451539..451814 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF556_RS02025 (NF556_02025) 447057..448220 + 1164 WP_252593842.1 energy-coupling factor transporter transmembrane component T -
NF556_RS02030 (NF556_02030) 448217..449995 + 1779 WP_252593843.1 ABC transporter ATP-binding protein -
NF556_RS02035 (NF556_02035) 449992..450894 + 903 WP_252593844.1 ECF transporter S component -
NF556_RS02040 (NF556_02040) 451314..451523 - 210 WP_252593845.1 hypothetical protein -
NF556_RS02045 (NF556_02045) 451539..451814 + 276 WP_252593846.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NF556_RS02050 (NF556_02050) 451811..452209 + 399 WP_252593847.1 type II toxin-antitoxin system VapC family toxin Toxin
NF556_RS02055 (NF556_02055) 452193..453062 - 870 WP_252593848.1 alpha/beta hydrolase -
NF556_RS02060 (NF556_02060) 453252..454400 - 1149 WP_252593849.1 pyridoxal phosphate-dependent aminotransferase -
NF556_RS02065 (NF556_02065) 454484..455122 - 639 WP_252593850.1 uracil phosphoribosyltransferase -
NF556_RS02070 (NF556_02070) 455133..456095 - 963 WP_252593851.1 WYL domain-containing protein -
NF556_RS02075 (NF556_02075) 456214..456630 + 417 WP_252593852.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-38)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14105.07 Da        Isoelectric Point: 5.5213

>T248938 WP_252593847.1 NZ_CP099489:451811-452209 [Ornithinimicrobium sp. HY1793]
VTALYVDSSALCKLVAQEEHTAAMHRLWTTHDGDLVSSDLARTEVMRQAGRCDPPRSTEARAVLDALVLVPVLTRIAQGA
GTLGPPSLRSLDALHLMTALELGDDLAGVVTYDDRQAEAARHLGLPVVTPRS

Download         Length: 399 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9543.79 Da        Isoelectric Point: 7.0141

>AT248938 WP_252593846.1 NZ_CP099489:451539-451814 [Ornithinimicrobium sp. HY1793]
MSSVGIRELRQSASAVVARAAAGETITITDRGRPVAQIGPRTPNGLHALREQGVVREPRASAADLPLPAPLPDGAPSLGQ
LLESDREERLT

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References