Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 75733..76418 Replicon plasmid pTT14-2
Accession NZ_CP099473
Organism Roseomonas mucosa strain TT14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NF552_RS22500 Protein ID WP_252572612.1
Coordinates 76026..76418 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NF552_RS22495 Protein ID WP_252572611.1
Coordinates 75733..76014 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF552_RS22465 (NF552_22465) 71011..71451 - 441 WP_252572606.1 hypothetical protein -
NF552_RS22475 (NF552_22475) 72855..73013 - 159 WP_252572607.1 IcmT/TraK family protein -
NF552_RS22480 (NF552_22480) 73013..74182 - 1170 WP_252572608.1 ATPase, T2SS/T4P/T4SS family -
NF552_RS22485 (NF552_22485) 74179..75144 - 966 WP_252572609.1 type IV secretory system conjugative DNA transfer family protein -
NF552_RS22490 (NF552_22490) 75137..75610 - 474 WP_252572610.1 DotD/TraH family lipoprotein -
NF552_RS22495 (NF552_22495) 75733..76014 + 282 WP_252572611.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NF552_RS22500 (NF552_22500) 76026..76418 + 393 WP_252572612.1 type II toxin-antitoxin system VapC family toxin Toxin
NF552_RS22505 (NF552_22505) 76469..78667 - 2199 WP_252572613.1 ATP-binding protein -
NF552_RS22510 (NF552_22510) 78764..80386 - 1623 WP_252572586.1 ISL3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..204011 204011


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-118)

Antitoxin

SpoVT-AbrB domain

(25-64)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13668.76 Da        Isoelectric Point: 5.8782

>T248935 WP_252572612.1 NZ_CP099473:76026-76418 [Roseomonas mucosa]
MLDTNIVSDLIRNPSGTAARKARAAGAAVCVSIIVAAELRYGCAKKGSPRLLERVEAFLDAVPVMALEVPADAEYGGLRA
ELEAAGQPIGGNDLLIAAHAYALEATLVTANVGEFRRIRGLRVENWLTPG

Download         Length: 393 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10675.20 Da        Isoelectric Point: 6.4692

>AT248935 WP_252572611.1 NZ_CP099473:75733-76014 [Roseomonas mucosa]
MSGIPLPGRSRHAAIQPHPRQVRLFRNNRNQAVRIPVEFELPGNEAIISRDGDRLILEPVRSKNLSVLLDSWEPMEESLP
DIDDRPLVTRDIF

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References