248933

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 8180441..8180973 Replicon chromosome
Accession NZ_CP099468
Organism Streptomyces phaeoluteigriseus strain Qhu-M197

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFX46_RS36100 Protein ID WP_289782118.1
Coordinates 8180441..8180704 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFX46_RS36105 Protein ID WP_252555145.1
Coordinates 8180701..8180973 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFX46_RS36080 (NFX46_36080) 8175840..8176997 - 1158 WP_289782117.1 acyl-CoA dehydrogenase -
NFX46_RS36085 (NFX46_36085) 8177204..8178547 + 1344 WP_252555136.1 UDP-glucose/GDP-mannose dehydrogenase family protein -
NFX46_RS36090 (NFX46_36090) 8178778..8179185 + 408 WP_252555139.1 VOC family protein -
NFX46_RS36095 (NFX46_36095) 8179214..8180338 - 1125 WP_252555142.1 dipeptidase -
NFX46_RS36100 (NFX46_36100) 8180441..8180704 - 264 WP_289782118.1 Txe/YoeB family addiction module toxin Toxin
NFX46_RS36105 (NFX46_36105) 8180701..8180973 - 273 WP_252555145.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NFX46_RS36110 (NFX46_36110) 8181051..8182229 - 1179 WP_252555148.1 dipeptidase -
NFX46_RS36115 (NFX46_36115) 8182235..8182765 - 531 WP_073498506.1 5-(carboxyamino)imidazole ribonucleotide mutase -
NFX46_RS36120 (NFX46_36120) 8182762..8183904 - 1143 WP_107439587.1 5-(carboxyamino)imidazole ribonucleotide synthase -
NFX46_RS36125 (NFX46_36125) 8184083..8184601 + 519 WP_252555150.1 GtrA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10499.87 Da        Isoelectric Point: 8.5122

>T248933 WP_289782118.1 NZ_CP099468:c8180704-8180441 [Streptomyces phaeoluteigriseus]
VRSVHFDPDAWEDFLFWLGSDRRMARRITRLIGEIQRDPFTGIGKPEPLKGDLSGYWSRRIDDEHRLVYRADDKELKILK
ARYHYHD

Download         Length: 264 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10097.41 Da        Isoelectric Point: 5.1634

>AT248933 WP_252555145.1 NZ_CP099468:c8180973-8180701 [Streptomyces phaeoluteigriseus]
MTISASEARRDLFPLIKRVNDDHMPVRISSKGGDAVLMSADDYEAWQETVYLLRSPANARRLMEAVARDKAGRSTVVKSF
EELRDLAGDE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References