248928

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 5230150..5230657 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name relB Uniprot ID A0A6H2BW57
Locus tag NG743_RS23875 Protein ID WP_027401524.1
Coordinates 5230150..5230410 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A6H2BVA9
Locus tag NG743_RS23880 Protein ID WP_027401523.1
Coordinates 5230403..5230657 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS23855 (NG743_23740) 5225161..5226282 + 1122 WP_257121035.1 bacteriohopanetetrol glucosamine biosynthesis glycosyltransferase HpnI -
NG743_RS23860 (NG743_23745) 5227067..5227684 - 618 WP_257121036.1 CAP family protein -
NG743_RS23865 (NG743_23750) 5227797..5228540 + 744 WP_027401526.1 sirohydrochlorin chelatase -
NG743_RS23870 (NG743_23755) 5228533..5229288 + 756 WP_193964702.1 uroporphyrinogen-III C-methyltransferase -
NG743_RS23875 (NG743_23760) 5230150..5230410 - 261 WP_027401524.1 Txe/YoeB family addiction module toxin Toxin
NG743_RS23880 (NG743_23765) 5230403..5230657 - 255 WP_027401523.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NG743_RS23885 (NG743_23770) 5230834..5231133 + 300 WP_257121037.1 hypothetical protein -
NG743_RS23890 (NG743_23775) 5231408..5231530 + 123 WP_236630549.1 hypothetical protein -
NG743_RS23895 (NG743_23780) 5231937..5232122 + 186 WP_152540422.1 hypothetical protein -
NG743_RS23900 5232849..5232974 - 126 WP_257121038.1 hypothetical protein -
NG743_RS23905 (NG743_23785) 5233012..5234289 + 1278 WP_257121039.1 phosphoribosylamine--glycine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10336.87 Da        Isoelectric Point: 7.9759

>T248928 WP_027401524.1 NZ_CP099464:c5230410-5230150 [Dolichospermum heterosporum TAC447]
MSRMLAWTDEAWGNYLYWQGQDKKTLKRINKLIEETMRMPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVDDVYVTII
SCRYHY

Download         Length: 261 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9554.87 Da        Isoelectric Point: 5.0623

>AT248928 WP_027401523.1 NZ_CP099464:c5230657-5230403 [Dolichospermum heterosporum TAC447]
MKIISFSEARNSLKTVLDQVTEDADYTIITRRDADDTVVMSLEFFNSLMETVHLLKSPANAAHLERSIAQFKQGKVVQRD
LLNE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6H2BW57

Antitoxin

Source ID Structure
AlphaFold DB A0A6H2BVA9

References