Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 4934571..4935463 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag NG743_RS22330 Protein ID WP_257120922.1
Coordinates 4934571..4935014 (-) Length 148 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag NG743_RS22335 Protein ID WP_027401755.1
Coordinates 4935011..4935463 (-) Length 151 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS22315 (NG743_22205) 4930047..4930805 - 759 WP_257120919.1 type I-D CRISPR-associated protein Cas5/Csc1 -
NG743_RS22320 (NG743_22210) 4930809..4931834 - 1026 WP_257120920.1 type I-D CRISPR-associated protein Cas7/Csc2 -
NG743_RS22325 (NG743_22215) 4931852..4934578 - 2727 WP_257120921.1 CRISPR-associated protein Csc3 -
NG743_RS22330 (NG743_22220) 4934571..4935014 - 444 WP_257120922.1 DUF86 domain-containing protein Toxin
NG743_RS22335 (NG743_22225) 4935011..4935463 - 453 WP_027401755.1 nucleotidyltransferase domain-containing protein Antitoxin
NG743_RS22340 (NG743_22230) 4935493..4935969 - 477 WP_257122172.1 DUF1016 domain-containing protein -
NG743_RS22345 (NG743_22235) 4935946..4936140 - 195 Protein_4418 DUF433 domain-containing protein -
NG743_RS22350 (NG743_22240) 4936297..4937178 + 882 WP_257120923.1 WYL domain-containing protein -
NG743_RS22355 (NG743_22245) 4937630..4937956 + 327 WP_051424266.1 hypothetical protein -
NG743_RS22360 (NG743_22250) 4937939..4938553 - 615 WP_257120924.1 K(+)-transporting ATPase subunit C -
NG743_RS22365 (NG743_22255) 4938553..4938747 - 195 WP_257120925.1 potassium-transporting ATPase subunit F -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(18-133)

Antitoxin

Polymerase beta, nucleotidyltransferase

(23-112)


Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 17006.51 Da        Isoelectric Point: 4.7523

>T248927 WP_257120922.1 NZ_CP099464:c4935014-4934571 [Dolichospermum heterosporum TAC447]
MTNIEPVIIETRLELIGRYLDHLKKFAGLSLNDYLSSFEQQLITERLLQLMTQAAIDINDHILSKLNPGKSYTNFEAFIE
LGKYQIITPELAKQIAPSSGLRNRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEKEND

Download         Length: 444 bp

Antitoxin


Download         Length: 151 a.a.        Molecular weight: 17333.83 Da        Isoelectric Point: 5.6985

>AT248927 WP_027401755.1 NZ_CP099464:c4935463-4935011 [Dolichospermum heterosporum TAC447]
MQNNTSSIIEIQQLSSQIPERIPYLKMLVLFGSRSTSNTNANSDWDFAVLCDEEKYNLYVQDHPLALFAIPGILGEIFKI
NSDNIDIVELNHCSKLIAHFVARDGKVLYENQADEFEKFKQRVLLSNTEIKKIEKTKLKNIENFLQRWGV

Download         Length: 453 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References