Detailed information of TA system
Overview
TA module
| Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
| Location | 4934571..4935463 | Replicon | chromosome |
| Accession | NZ_CP099464 | ||
| Organism | Dolichospermum heterosporum TAC447 strain NIES-1697 | ||
Toxin (Protein)
| Gene name | hepT | Uniprot ID | - |
| Locus tag | NG743_RS22330 | Protein ID | WP_257120922.1 |
| Coordinates | 4934571..4935014 (-) | Length | 148 a.a. |
Antitoxin (Protein)
| Gene name | mntA | Uniprot ID | - |
| Locus tag | NG743_RS22335 | Protein ID | WP_027401755.1 |
| Coordinates | 4935011..4935463 (-) | Length | 151 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NG743_RS22315 (NG743_22205) | 4930047..4930805 | - | 759 | WP_257120919.1 | type I-D CRISPR-associated protein Cas5/Csc1 | - |
| NG743_RS22320 (NG743_22210) | 4930809..4931834 | - | 1026 | WP_257120920.1 | type I-D CRISPR-associated protein Cas7/Csc2 | - |
| NG743_RS22325 (NG743_22215) | 4931852..4934578 | - | 2727 | WP_257120921.1 | CRISPR-associated protein Csc3 | - |
| NG743_RS22330 (NG743_22220) | 4934571..4935014 | - | 444 | WP_257120922.1 | DUF86 domain-containing protein | Toxin |
| NG743_RS22335 (NG743_22225) | 4935011..4935463 | - | 453 | WP_027401755.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
| NG743_RS22340 (NG743_22230) | 4935493..4935969 | - | 477 | WP_257122172.1 | DUF1016 domain-containing protein | - |
| NG743_RS22345 (NG743_22235) | 4935946..4936140 | - | 195 | Protein_4418 | DUF433 domain-containing protein | - |
| NG743_RS22350 (NG743_22240) | 4936297..4937178 | + | 882 | WP_257120923.1 | WYL domain-containing protein | - |
| NG743_RS22355 (NG743_22245) | 4937630..4937956 | + | 327 | WP_051424266.1 | hypothetical protein | - |
| NG743_RS22360 (NG743_22250) | 4937939..4938553 | - | 615 | WP_257120924.1 | K(+)-transporting ATPase subunit C | - |
| NG743_RS22365 (NG743_22255) | 4938553..4938747 | - | 195 | WP_257120925.1 | potassium-transporting ATPase subunit F | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 148 a.a. Molecular weight: 17006.51 Da Isoelectric Point: 4.7523
>T248927 WP_257120922.1 NZ_CP099464:c4935014-4934571 [Dolichospermum heterosporum TAC447]
MTNIEPVIIETRLELIGRYLDHLKKFAGLSLNDYLSSFEQQLITERLLQLMTQAAIDINDHILSKLNPGKSYTNFEAFIE
LGKYQIITPELAKQIAPSSGLRNRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEKEND
MTNIEPVIIETRLELIGRYLDHLKKFAGLSLNDYLSSFEQQLITERLLQLMTQAAIDINDHILSKLNPGKSYTNFEAFIE
LGKYQIITPELAKQIAPSSGLRNRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEKEND
Download Length: 444 bp
Antitoxin
Download Length: 151 a.a. Molecular weight: 17333.83 Da Isoelectric Point: 5.6985
>AT248927 WP_027401755.1 NZ_CP099464:c4935463-4935011 [Dolichospermum heterosporum TAC447]
MQNNTSSIIEIQQLSSQIPERIPYLKMLVLFGSRSTSNTNANSDWDFAVLCDEEKYNLYVQDHPLALFAIPGILGEIFKI
NSDNIDIVELNHCSKLIAHFVARDGKVLYENQADEFEKFKQRVLLSNTEIKKIEKTKLKNIENFLQRWGV
MQNNTSSIIEIQQLSSQIPERIPYLKMLVLFGSRSTSNTNANSDWDFAVLCDEEKYNLYVQDHPLALFAIPGILGEIFKI
NSDNIDIVELNHCSKLIAHFVARDGKVLYENQADEFEKFKQRVLLSNTEIKKIEKTKLKNIENFLQRWGV
Download Length: 453 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|