248922

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 3578519..3579078 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NG743_RS16045 Protein ID WP_027403706.1
Coordinates 3578740..3579078 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NG743_RS16040 Protein ID WP_027403705.1
Coordinates 3578519..3578743 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS16010 (NG743_15925) 3573602..3573796 + 195 WP_257120424.1 DUF433 domain-containing protein -
NG743_RS16015 (NG743_15930) 3573793..3574308 + 516 WP_257120425.1 hypothetical protein -
NG743_RS16020 (NG743_15935) 3574494..3576140 - 1647 WP_027403701.1 Ppx/GppA phosphatase family protein -
NG743_RS16025 (NG743_15940) 3576232..3577113 + 882 WP_027403702.1 4-hydroxybenzoate solanesyltransferase -
NG743_RS16030 (NG743_15945) 3577239..3577817 + 579 WP_027403703.1 hypothetical protein -
NG743_RS16035 (NG743_15950) 3578295..3578486 + 192 WP_027403704.1 hypothetical protein -
NG743_RS16040 (NG743_15955) 3578519..3578743 + 225 WP_027403705.1 DUF433 domain-containing protein Antitoxin
NG743_RS16045 (NG743_15960) 3578740..3579078 + 339 WP_027403706.1 DUF5615 family PIN-like protein Toxin
NG743_RS16050 (NG743_15965) 3579763..3580065 + 303 WP_152540481.1 hypothetical protein -
NG743_RS16055 (NG743_15970) 3580010..3581137 + 1128 WP_257120426.1 hypothetical protein -
NG743_RS16060 (NG743_15975) 3581361..3581585 + 225 WP_027403709.1 type II toxin-antitoxin system HicA family toxin -
NG743_RS16065 (NG743_15980) 3581582..3581809 + 228 WP_027403710.1 type II toxin-antitoxin system HicB family antitoxin -
NG743_RS16070 (NG743_15985) 3581865..3582197 - 333 WP_027403711.1 DUF86 domain-containing protein -
NG743_RS16075 (NG743_15990) 3582194..3582484 - 291 WP_027403712.1 nucleotidyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12726.86 Da        Isoelectric Point: 4.8101

>T248922 WP_027403706.1 NZ_CP099464:3578740-3579078 [Dolichospermum heterosporum TAC447]
MKIWIDAQLPPTLADWITNTFAIEAFSLKEIGLRDAKDIDIFEAAKIANVIIMTKDSDFVDLVCRLGTPPQIIWLTCGNV
TNRNLRQLLNFTLHDALEKLRQGEMIVEINKS

Download         Length: 339 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8391.76 Da        Isoelectric Point: 4.3466

>AT248922 WP_027403705.1 NZ_CP099464:3578519-3578743 [Dolichospermum heterosporum TAC447]
MNELLTRITQIPGQCGGRPCIRGMRIRVSDILEMLAENVSVNEILEDFPDLELEDIQACLIFAARRTDFVRLTA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References