Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 2206517..2207216 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NG743_RS09820 Protein ID WP_257122139.1
Coordinates 2206517..2206897 (+) Length 127 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NG743_RS09825 Protein ID WP_027402638.1
Coordinates 2206890..2207216 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS09785 (NG743_09735) 2201556..2202620 + 1065 WP_193963740.1 metal-dependent hydrolase -
NG743_RS09790 (NG743_09740) 2202639..2203481 + 843 WP_257121920.1 pentapeptide repeat-containing protein -
NG743_RS09795 (NG743_09745) 2204190..2204387 + 198 WP_027402632.1 pentapeptide repeat-containing protein -
NG743_RS09800 (NG743_09750) 2204742..2205020 + 279 WP_027402633.1 hypothetical protein -
NG743_RS09805 (NG743_09755) 2205231..2205545 + 315 WP_027402634.1 helix-turn-helix transcriptional regulator -
NG743_RS09810 (NG743_09760) 2205535..2206080 + 546 WP_027402635.1 pentapeptide repeat-containing protein -
NG743_RS09815 (NG743_09765) 2206173..2206367 + 195 WP_236630580.1 hypothetical protein -
NG743_RS09820 (NG743_09770) 2206517..2206897 + 381 WP_257122139.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NG743_RS09825 (NG743_09775) 2206890..2207216 + 327 WP_027402638.1 helix-turn-helix transcriptional regulator Antitoxin
NG743_RS09830 (NG743_09780) 2207384..2207611 + 228 WP_027402639.1 DUF87 domain-containing protein -
NG743_RS09835 (NG743_09785) 2208171..2208764 + 594 WP_257121921.1 hypothetical protein -
NG743_RS09840 (NG743_09790) 2209313..2209654 + 342 WP_027402640.1 hypothetical protein -
NG743_RS09845 (NG743_09795) 2209671..2210336 - 666 WP_257121922.1 DUF2834 domain-containing protein -
NG743_RS09850 (NG743_09800) 2210350..2211426 - 1077 WP_027402642.1 heat-inducible transcriptional repressor HrcA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-89)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14212.15 Da        Isoelectric Point: 6.4880

>T248918 WP_257122139.1 NZ_CP099464:2206517-2206897 [Dolichospermum heterosporum TAC447]
INEKPLKWVASALDDLKEFPEDVQDVMGYALDLAQHGQKHPDAKPLKGFPESGVVEIVDDFDGDTYRAIYTVKFKGVIYL
LHSFQKKSKHGIATPQQDIDLVRKRLKTAELDYLQETAQKNGVKNG

Download         Length: 381 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11898.72 Da        Isoelectric Point: 9.0771

>AT248918 WP_027402638.1 NZ_CP099464:2206890-2207216 [Dolichospermum heterosporum TAC447]
MDSENRITVSSGNVFADLGLANSEERLLKAELARKISEIINSQKLTQVQAAEILGIDQPKVSLLIRGRLSGFSTDRLMAY
LNKLGSDVEITVKPKPENHKFARTTVVC

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References