248916

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 1749235..1749745 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NG743_RS07925 Protein ID WP_027404113.1
Coordinates 1749235..1749513 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NG743_RS07930 Protein ID WP_257121822.1
Coordinates 1749503..1749745 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS07895 (NG743_07860) 1744376..1744648 - 273 WP_027404119.1 hypothetical protein -
NG743_RS07900 (NG743_07865) 1744702..1745748 - 1047 WP_027404118.1 ABC transporter permease -
NG743_RS07905 (NG743_07870) 1745922..1746440 - 519 WP_027404117.1 adenine phosphoribosyltransferase -
NG743_RS07910 (NG743_07875) 1746726..1747352 + 627 WP_027404116.1 DUF3038 domain-containing protein -
NG743_RS07915 (NG743_07880) 1747363..1748793 + 1431 WP_027404115.1 DUF4335 domain-containing protein -
NG743_RS07920 (NG743_07885) 1748919..1749194 + 276 WP_027404114.1 lipopolysaccharide assembly protein LapA domain-containing protein -
NG743_RS07925 (NG743_07890) 1749235..1749513 - 279 WP_027404113.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
NG743_RS07930 (NG743_07895) 1749503..1749745 - 243 WP_257121822.1 ribbon-helix-helix protein, CopG family Antitoxin
NG743_RS07935 (NG743_07900) 1749946..1750224 + 279 WP_027404111.1 transcriptional regulator -
NG743_RS07940 (NG743_07905) 1750276..1750707 + 432 WP_257121823.1 DUF29 domain-containing protein -
NG743_RS07945 (NG743_07910) 1750783..1751829 - 1047 WP_027404109.1 Type 1 glutamine amidotransferase-like domain-containing protein -
NG743_RS07950 (NG743_07915) 1751955..1753142 - 1188 WP_027404108.1 glycosyltransferase family 4 protein -
NG743_RS07955 (NG743_07920) 1753503..1754078 - 576 WP_257121824.1 leucyl/phenylalanyl-tRNA--protein transferase -
NG743_RS07960 (NG743_07925) 1754132..1754461 + 330 WP_027404106.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10843.58 Da        Isoelectric Point: 10.1944

>T248916 WP_027404113.1 NZ_CP099464:c1749513-1749235 [Dolichospermum heterosporum TAC447]
MRVKWLRQALRNLKQAHNYVFPENPTAAQELILKIQNAANQLENYPFMGKSGRVDGTRELIISNSPYMIIYRVKEETVEI
LRILHTSKRYPE

Download         Length: 279 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8919.96 Da        Isoelectric Point: 4.7769

>AT248916 WP_257121822.1 NZ_CP099464:c1749745-1749503 [Dolichospermum heterosporum TAC447]
MSKENITFRIDSSKKAAIDALAKGINRDRSYILNEAVNAYLEMYQWQIKEIHQGIAEAEAGDFASDEEVTATFAKLNHAG

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References