248915

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1565121..1565670 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NG743_RS07135 Protein ID WP_027404251.1
Coordinates 1565332..1565670 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NG743_RS07130 Protein ID WP_027404252.1
Coordinates 1565121..1565345 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS07115 (NG743_07095) 1560888..1562479 - 1592 Protein_1416 IS1634 family transposase -
NG743_RS07120 (NG743_07100) 1563098..1564066 - 969 WP_257121760.1 arsenosugar biosynthesis arsenite methyltransferase ArsM -
NG743_RS07125 (NG743_07105) 1564346..1564963 + 618 WP_027404253.1 TMEM165/GDT1 family protein -
NG743_RS07130 (NG743_07110) 1565121..1565345 + 225 WP_027404252.1 CopG family transcriptional regulator Antitoxin
NG743_RS07135 (NG743_07115) 1565332..1565670 + 339 WP_027404251.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NG743_RS07140 (NG743_07120) 1565887..1566021 + 135 Protein_1421 TMEM165/GDT1 family protein -
NG743_RS07145 (NG743_07125) 1566106..1566483 - 378 WP_257122127.1 TaqI-like C-terminal specificity domain-containing protein -
NG743_RS07150 (NG743_07130) 1566556..1567008 - 453 WP_257121761.1 hypothetical protein -
NG743_RS07155 (NG743_07135) 1567037..1567813 - 777 WP_257121762.1 hypothetical protein -
NG743_RS07160 (NG743_07140) 1568347..1569240 - 894 WP_193962915.1 tetratricopeptide repeat protein -
NG743_RS07165 (NG743_07145) 1569632..1570624 + 993 WP_027404248.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12339.23 Da        Isoelectric Point: 6.9774

>T248915 WP_027404251.1 NZ_CP099464:1565332-1565670 [Dolichospermum heterosporum TAC447]
MKRGEIYLANLSPAVGSEMDKRRPVLIVSNDANNNASTTVTIVPITSNMSRVYPFEVLLNPEDSGLYKTSKVQAQQIRTI
SKQRILGDVVGCLSQELIDLVNDAIKLHLALE

Download         Length: 339 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8496.56 Da        Isoelectric Point: 4.0745

>AT248915 WP_027404252.1 NZ_CP099464:1565121-1565345 [Dolichospermum heterosporum TAC447]
MQAEKLSISLPSSLVQFIENYKLTKGCKSRSQVIELAIELLRYQELEQAYREAAAEFDPEWDLTVGDGLTDETW

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References