248913

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-UPF0150
Location 1357766..1358181 Replicon chromosome
Accession NZ_CP099464
Organism Dolichospermum heterosporum TAC447 strain NIES-1697

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NG743_RS06020 Protein ID WP_257122125.1
Coordinates 1357766..1357957 (+) Length 64 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NG743_RS06025 Protein ID WP_041458210.1
Coordinates 1357966..1358181 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG743_RS05995 (NG743_05975) 1353373..1355058 - 1686 WP_257121692.1 hypothetical protein -
NG743_RS06000 (NG743_05980) 1355245..1355502 + 258 Protein_1193 hypothetical protein -
NG743_RS06005 (NG743_05985) 1355682..1356188 - 507 WP_257121693.1 hypothetical protein -
NG743_RS06010 (NG743_05990) 1356192..1356365 - 174 WP_257121694.1 hypothetical protein -
NG743_RS06015 (NG743_05995) 1356536..1357714 - 1179 WP_257121695.1 HEAT repeat domain-containing protein -
NG743_RS06020 (NG743_06000) 1357766..1357957 + 192 WP_257122125.1 type II toxin-antitoxin system HicA family toxin Toxin
NG743_RS06025 (NG743_06005) 1357966..1358181 + 216 WP_041458210.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NG743_RS06030 (NG743_06010) 1358208..1358825 + 618 WP_257121696.1 type I restriction endonuclease subunit R -
NG743_RS06035 (NG743_06015) 1358863..1359297 + 435 WP_015078603.1 DUF29 domain-containing protein -
NG743_RS06040 (NG743_06020) 1359458..1362139 + 2682 WP_027404416.1 RNA helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-63)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(7-62)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7253.42 Da        Isoelectric Point: 9.4836

>T248913 WP_257122125.1 NZ_CP099464:1357766-1357957 [Dolichospermum heterosporum TAC447]
IQYYNYREIVTILEEVGWYIDRTIVSHRILKHQSKSGIVVIPGKPSDDIPVGTLSSIWKQAKL

Download         Length: 192 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7765.82 Da        Isoelectric Point: 3.8077

>AT248913 WP_041458210.1 NZ_CP099464:1357966-1358181 [Dolichospermum heterosporum TAC447]
MIEYTVIYERGQTNWGAYVPDLPGCVSIGDTLAEVQENIKEAIALYLEVLKEDGQPIPEPSTEVGKVAVTI

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References