Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 1034748..1035721 Replicon chromosome
Accession NZ_CP099450
Organism Bacillus pacificus strain ANSB901

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag NE411_RS05395 Protein ID WP_014893739.1
Coordinates 1034748..1035485 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A151UPU1
Locus tag NE411_RS05400 Protein ID WP_000588714.1
Coordinates 1035593..1035721 (+) Length 43 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE411_RS05370 (NE411_05355) 1029830..1030612 + 783 WP_000381777.1 class I SAM-dependent methyltransferase -
NE411_RS05375 (NE411_05360) 1030790..1032475 - 1686 WP_011040340.1 alpha-keto acid decarboxylase family protein -
NE411_RS05380 (NE411_05365) 1032583..1033065 + 483 WP_000191907.1 MarR family winged helix-turn-helix transcriptional regulator -
NE411_RS05385 (NE411_05370) 1033172..1033336 + 165 Protein_1072 transposase -
NE411_RS05390 (NE411_05375) 1033673..1034410 + 738 WP_000594137.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
NE411_RS05395 (NE411_05380) 1034748..1035485 + 738 WP_014893739.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
NE411_RS05400 (NE411_05385) 1035593..1035721 + 129 WP_000588714.1 hypothetical protein Antitoxin
NE411_RS05405 (NE411_05390) 1035794..1035970 + 177 WP_000852590.1 stage II sporulation protein SB -
NE411_RS05410 (NE411_05395) 1035989..1036378 - 390 WP_000714180.1 YxeA family protein -
NE411_RS05415 (NE411_05400) 1036595..1038064 + 1470 WP_000287562.1 beta-Ala-His dipeptidase -
NE411_RS05420 (NE411_05405) 1038265..1038871 + 607 Protein_1079 CatB-related O-acetyltransferase -
NE411_RS05425 (NE411_05410) 1039315..1040628 + 1314 WP_000677730.1 D-alanyl-D-alanine carboxypeptidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28351.07 Da        Isoelectric Point: 8.2998

>T248908 WP_014893739.1 NZ_CP099450:1034748-1035485 [Bacillus pacificus]
VISNIRIGLFILAIVFLVLVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMVKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNVFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIIVPFEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

Antitoxin


Download         Length: 43 a.a.        Molecular weight: 5024.48 Da        Isoelectric Point: 4.0932

>AT248908 WP_000588714.1 NZ_CP099450:1035593-1035721 [Bacillus pacificus]
VIKDYDNDFFKKDNEDTTDFSLIKGDTLQQVEELEEELKRKS

Download         Length: 129 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A151UPU1

References