Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011409..2011554 Replicon chromosome
Accession NZ_CP099413
Organism Klebsiella pneumoniae strain 33367

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011445..2011547 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011409..2011554 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE847_RS09840 (NE847_09840) 2006539..2008599 + 2061 WP_004151449.1 oligopeptidase B -
NE847_RS09845 (NE847_09845) 2008603..2009262 - 660 WP_002911407.1 exodeoxyribonuclease X -
NE847_RS09850 (NE847_09850) 2009341..2009571 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NE847_RS09855 (NE847_09855) 2009684..2010058 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NE847_RS09860 (NE847_09860) 2010062..2010931 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NE847_RS09865 (NE847_09865) 2010948..2011286 + 339 WP_002911404.1 YebY family protein -
- 2011409..2011554 - 146 - - Antitoxin
- 2011445..2011547 + 103 - - Toxin
NE847_RS09870 (NE847_09870) 2011922..2012065 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NE847_RS09875 (NE847_09875) 2012170..2013138 - 969 WP_004151446.1 VirK/YbjX family protein -
NE847_RS09880 (NE847_09880) 2013295..2013948 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NE847_RS09885 (NE847_09885) 2013945..2014136 - 192 WP_002911395.1 YebW family protein -
NE847_RS09890 (NE847_09890) 2014234..2014473 - 240 WP_002911393.1 YebV family protein -
NE847_RS09895 (NE847_09895) 2014589..2016022 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T248889 NZ_CP099413:2011445-2011547 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT248889 NZ_CP099413:c2011554-2011409 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References