Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 687160..687758 Replicon plasmid pRsp_Pop5_1
Accession NZ_CP099402
Organism Rhizobium sp. Pop5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NE852_RS31240 Protein ID WP_258157024.1
Coordinates 687160..687453 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID K0VFN6
Locus tag NE852_RS31245 Protein ID WP_008537324.1
Coordinates 687450..687758 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE852_RS31220 (NE852_31130) 682648..683580 + 933 WP_008523369.1 FAD-binding protein -
NE852_RS31225 (NE852_31135) 683634..684542 + 909 WP_008523371.1 alpha/beta hydrolase -
NE852_RS31230 685773..685904 + 132 Protein_624 hypothetical protein -
NE852_RS31235 (NE852_31145) 686292..686972 + 681 WP_258157201.1 methyl-accepting chemotaxis protein -
NE852_RS31240 (NE852_31150) 687160..687453 - 294 WP_258157024.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NE852_RS31245 (NE852_31155) 687450..687758 - 309 WP_008537324.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NE852_RS31250 (NE852_31160) 687967..689919 - 1953 WP_258157025.1 acetate--CoA ligase -
NE852_RS31255 (NE852_31165) 690077..691411 - 1335 WP_008523382.1 FAD-binding oxidoreductase -
NE852_RS31260 (NE852_31170) 691587..692465 - 879 WP_037170748.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..951562 951562


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-58)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10615.10 Da        Isoelectric Point: 5.7996

>T248883 WP_258157024.1 NZ_CP099402:c687453-687160 [Rhizobium sp. Pop5]
VKLTWSAFALSDRDAIFTYIEGENPSAAILVDERIVAAVRRLIDFPASGRVGRIAGTRELVINGTPYVAAYSFNETAVRI
LRVLHGAQEWPDTLPTG

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11012.35 Da        Isoelectric Point: 5.1570

>AT248883 WP_008537324.1 NZ_CP099402:c687758-687450 [Rhizobium sp. Pop5]
MAANALVQTRIDAEIRDRASAVLGNMGLTVSDAVRILLTRTANEGALPLELLSGSEAHDAWFRAKVLEALNDTRPDVSDD
EVETHFAERRAAARLNAGARKS

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB K0VFN6

References