Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 663759..664339 Replicon plasmid pRsp_Pop5_1
Accession NZ_CP099402
Organism Rhizobium sp. Pop5

Toxin (Protein)


Gene name vapC Uniprot ID K0WHJ4
Locus tag NE852_RS31125 Protein ID WP_008523320.1
Coordinates 663956..664339 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NE852_RS31120 Protein ID WP_258157020.1
Coordinates 663759..663959 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE852_RS31110 (NE852_31020) 659205..661040 - 1836 WP_008523293.1 HAMP domain-containing methyl-accepting chemotaxis protein -
NE852_RS31115 (NE852_31025) 661512..662810 - 1299 WP_258157018.1 Nramp family divalent metal transporter -
NE852_RS31120 (NE852_31030) 663759..663959 + 201 WP_258157020.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NE852_RS31125 (NE852_31035) 663956..664339 + 384 WP_008523320.1 type II toxin-antitoxin system VapC family toxin Toxin
NE852_RS31130 (NE852_31040) 664481..665110 - 630 WP_008523322.1 CoA transferase subunit B -
NE852_RS31135 (NE852_31045) 665111..665815 - 705 WP_008523324.1 CoA transferase subunit A -
NE852_RS31140 (NE852_31050) 665935..667071 - 1137 WP_128623493.1 saccharopine dehydrogenase NADP-binding domain-containing protein -
NE852_RS31145 (NE852_31055) 667247..668260 + 1014 WP_037170731.1 3-keto-5-aminohexanoate cleavage protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..951562 951562


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14214.28 Da        Isoelectric Point: 6.6041

>T248882 WP_008523320.1 NZ_CP099402:663956-664339 [Rhizobium sp. Pop5]
VILADTSIWIDHFRHADSELRRIIEDDRLLCHPAVIGELALGGLRDRSSVIAFLAAQREAFVATHDEVMMMIDRHSIFSM
GIGYTDAHLMASVLLDQRAALWTRDKRLRAAAEKAGASLHTPDNPRN

Download         Length: 384 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7194.36 Da        Isoelectric Point: 11.3760

>AT248882 WP_258157020.1 NZ_CP099402:663759-663959 [Rhizobium sp. Pop5]
MRSTINLDDILMERARSLTGTKETATLVRQALETLVRVESGKRLIALGGTMPDAEAAPRRRSAVAK

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K0WHJ4

Antitoxin

Source ID Structure

References