Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 559960..560678 Replicon chromosome
Accession NZ_CP099399
Organism Rhizobium sp. Pop5

Toxin (Protein)


Gene name vapC Uniprot ID K0VNE9
Locus tag NE852_RS04875 Protein ID WP_008529505.1
Coordinates 559960..560418 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID K0VS40
Locus tag NE852_RS04880 Protein ID WP_008529504.1
Coordinates 560415..560678 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE852_RS04850 (NE852_04830) 555160..555582 + 423 WP_128623565.1 DUF4279 domain-containing protein -
NE852_RS04855 (NE852_04835) 555753..557390 - 1638 WP_008529514.1 chaperonin GroEL -
NE852_RS04860 (NE852_04840) 557462..557758 - 297 WP_004675403.1 co-chaperone GroES -
NE852_RS04865 (NE852_04845) 558087..558935 + 849 WP_008529507.1 TIGR01459 family HAD-type hydrolase -
NE852_RS04870 (NE852_04850) 558950..559933 + 984 WP_008529506.1 bifunctional riboflavin kinase/FAD synthetase -
NE852_RS04875 (NE852_04855) 559960..560418 - 459 WP_008529505.1 type II toxin-antitoxin system VapC family toxin Toxin
NE852_RS04880 (NE852_04860) 560415..560678 - 264 WP_008529504.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NE852_RS04885 (NE852_04865) 561033..563939 + 2907 WP_008529503.1 isoleucine--tRNA ligase -
NE852_RS04890 (NE852_04870) 564071..564700 + 630 WP_008529502.1 hypothetical protein -
NE852_RS04895 (NE852_04875) 564749..565186 - 438 WP_037172284.1 nucleoside deaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-67)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17163.43 Da        Isoelectric Point: 6.7307

>T248877 WP_008529505.1 NZ_CP099399:c560418-559960 [Rhizobium sp. Pop5]
VIGWLLDTNVIAALINPNGAPSVKSWAAAQDEEQMFISVLTLAEYDKGIENLPEDDQNRYRYIAARDALEERFSQRILSL
SDKAVRHWGSVSGRVKLRTGHTPPVIDTMLAVTAIEHNLYLATRNVKDKRFSGAAVFDPWTNDPDQFPLRRK

Download         Length: 459 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10168.71 Da        Isoelectric Point: 5.3065

>AT248877 WP_008529504.1 NZ_CP099399:c560678-560415 [Rhizobium sp. Pop5]
MRKVIEQSWKLEDAKARFSEVVRRARSEGPQRVTVRGKDSVVIISVEELEQLIKAEPKKPLVDFMESLALKELDIERERD
YGRDVEL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K0VNE9

Antitoxin

Source ID Structure
AlphaFold DB K0VS40

References