Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 3966829..3968240 Replicon chromosome
Accession NZ_CP099397
Organism Pseudomonas hydrolytica strain DSWY01

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag L1F06_RS18620 Protein ID WP_129481677.1
Coordinates 3967671..3968240 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag L1F06_RS18615 Protein ID WP_003246035.1
Coordinates 3966829..3967668 (-) Length 280 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1F06_RS18600 (L1F06_018600) 3963746..3964651 - 906 WP_129481674.1 GIDE domain-containing protein -
L1F06_RS18605 (L1F06_018605) 3964653..3965225 - 573 WP_129481675.1 LemA family protein -
L1F06_RS18610 (L1F06_018610) 3965416..3966753 + 1338 WP_129481676.1 imelysin family protein -
L1F06_RS18615 (L1F06_018615) 3966829..3967668 - 840 WP_003246035.1 AraC family transcriptional regulator Antitoxin
L1F06_RS18620 (L1F06_018620) 3967671..3968240 - 570 WP_129481677.1 GNAT family protein Toxin
L1F06_RS18625 (L1F06_018625) 3968441..3971929 + 3489 WP_129481678.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
L1F06_RS18630 (L1F06_018630) 3971972..3972790 - 819 WP_012019411.1 MerR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21260.39 Da        Isoelectric Point: 8.9246

>T248875 WP_129481677.1 NZ_CP099397:c3968240-3967671 [Pseudomonas hydrolytica]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQPLDWYRSALAELREQRALPFAIRLGEQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNASIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAAREGLLRNHRRLAD
GRLDDTVLYSITDQEWPQVRAALEARFGG

Download         Length: 570 bp

Antitoxin


Download         Length: 280 a.a.        Molecular weight: 30956.10 Da        Isoelectric Point: 7.7422

>AT248875 WP_003246035.1 NZ_CP099397:c3967668-3966829 [Pseudomonas hydrolytica]
MQPLTGSERARFSASDDLHGLELLSARFVEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELESPPAAPPMFHDSVHHDPLLASRLSALHRLLEDPHSEALQRQTLWREAMLELLQR
YARLPAPRGVGQEPRAVALAKELLASQLSEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLRQRRLEQARTLLRSGC
SALSVAMQLGFADQSHLSRQFKQTYGVSPGEYRSAVARG

Download         Length: 840 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References