Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT_toxin-BrnA
Location 4404072..4404650 Replicon chromosome
Accession NZ_CP099394
Organism Paraburkholderia bryophila strain CA002

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag NDK50_RS19965 Protein ID WP_272625700.1
Coordinates 4404372..4404650 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag NDK50_RS19960 Protein ID WP_272625698.1
Coordinates 4404072..4404332 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDK50_RS19940 (NDK50_19925) 4399163..4399915 + 753 WP_272625691.1 5-oxoprolinase subunit PxpA -
NDK50_RS19945 (NDK50_19930) 4400233..4400982 + 750 WP_111933434.1 DUF969 domain-containing protein -
NDK50_RS19950 (NDK50_19935) 4400979..4401935 + 957 WP_272625694.1 DUF979 domain-containing protein -
NDK50_RS19955 (NDK50_19940) 4402164..4403978 + 1815 WP_272625696.1 tetratricopeptide repeat protein -
NDK50_RS19960 (NDK50_19945) 4404072..4404332 - 261 WP_272625698.1 BrnA antitoxin family protein Antitoxin
NDK50_RS19965 (NDK50_19950) 4404372..4404650 - 279 WP_272625700.1 BrnT family toxin Toxin
NDK50_RS19970 (NDK50_19955) 4404854..4406029 - 1176 WP_272625702.1 TraB/GumN family protein -
NDK50_RS19975 (NDK50_19960) 4406022..4407041 - 1020 WP_272625704.1 peptide ABC transporter ATP-binding protein -
NDK50_RS19980 (NDK50_19965) 4407038..4408042 - 1005 WP_272625706.1 ABC transporter ATP-binding protein -
NDK50_RS19985 (NDK50_19970) 4408044..4408961 - 918 WP_272625708.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-82)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(25-78)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10922.43 Da        Isoelectric Point: 6.2241

>T248867 WP_272625700.1 NZ_CP099394:c4404650-4404372 [Paraburkholderia bryophila]
VLFEWDEIKNQINIRKHGIDFSDAIDVFNHPVLTALDQREDYGEERWIALGCISVVLGVVVYVERDENVLRIISARKATR
REITQYRQRVWH

Download         Length: 279 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10085.59 Da        Isoelectric Point: 10.2562

>AT248867 WP_272625698.1 NZ_CP099394:c4404332-4404072 [Paraburkholderia bryophila]
MVKKKSATDWKRLASSKDEQIDTSEMPELAGDFFERAELHVPPKQAVTMRLDADVLSWFKEQGQGYQTRINKLLRAYMMA
QQRRRP

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References