248851

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 4264128..4264810 Replicon chromosome
Accession NZ_CP099389
Organism Citrobacter braakii strain RHB02-E4-C01

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag NFJ24_RS20270 Protein ID WP_114263376.1
Coordinates 4264128..4264469 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NFJ24_RS20275 Protein ID WP_114263375.1
Coordinates 4264490..4264810 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ24_RS20240 (4260172) 4260172..4260534 + 363 WP_235117078.1 endoribonuclease SymE -
NFJ24_RS20245 (4260593) 4260593..4261078 - 486 WP_094760967.1 type VI secretion system tube protein TssD -
NFJ24_RS20250 (4261098) 4261098..4261430 - 333 WP_094760968.1 DUF1493 family protein -
NFJ24_RS20255 (4261424) 4261424..4261879 - 456 WP_235117079.1 hypothetical protein -
NFJ24_RS20260 (4262138) 4262138..4263010 + 873 WP_279266228.1 HNH endonuclease -
NFJ24_RS20265 (4263349) 4263349..4263993 + 645 WP_279266229.1 hypothetical protein -
NFJ24_RS20270 (4264128) 4264128..4264469 - 342 WP_114263376.1 TA system toxin CbtA family protein Toxin
NFJ24_RS20275 (4264490) 4264490..4264810 - 321 WP_114263375.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ24_RS20280 (4264829) 4264829..4265050 - 222 WP_279266230.1 DUF987 domain-containing protein -
NFJ24_RS20285 (4265059) 4265059..4265541 - 483 WP_114263374.1 DNA repair protein RadC -
NFJ24_RS20290 (4265550) 4265550..4266014 - 465 WP_279266231.1 antirestriction protein -
NFJ24_RS20295 (4266155) 4266155..4268998 - 2844 WP_279266232.1 Ag43/Cah family autotransporter adhesin -
NFJ24_RS20300 (4269071) 4269071..4269757 - 687 WP_047738081.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4261098..4297985 36887


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(6-105)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12773.84 Da        Isoelectric Point: 6.9769

>T248851 WP_114263376.1 NZ_CP099389:c4264469-4264128 [Citrobacter braakii]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEYIDAGISLANAVNFLVEKYELVRIDRRGF
SWQEQSPYLLAVDILQARQAIGLLRRSLNDAVL

Download         Length: 342 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12003.70 Da        Isoelectric Point: 7.3722

>AT248851 WP_114263375.1 NZ_CP099389:c4264810-4264490 [Citrobacter braakii]
MRSHVTWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVVFPHFISQMESMLTTGEMNPRHAHCVTLY
HNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References