248844

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 849125..849779 Replicon chromosome
Accession NZ_CP099389
Organism Citrobacter braakii strain RHB02-E4-C01

Toxin (Protein)


Gene name cptA Uniprot ID A0A7L6TYP6
Locus tag NFJ24_RS04125 Protein ID WP_047357821.1
Coordinates 849372..849779 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID R8WMJ6
Locus tag NFJ24_RS04120 Protein ID WP_016154349.1
Coordinates 849125..849391 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ24_RS04095 (844338) 844338..845771 - 1434 WP_235117298.1 6-phospho-beta-glucosidase BglA -
NFJ24_RS04100 (845892) 845892..846620 - 729 WP_049282170.1 MurR/RpiR family transcriptional regulator -
NFJ24_RS04105 (846673) 846673..846984 + 312 WP_016154352.1 N(4)-acetylcytidine aminohydrolase -
NFJ24_RS04110 (847148) 847148..847807 + 660 WP_016154351.1 hemolysin III family protein -
NFJ24_RS04115 (847887) 847887..848867 - 981 WP_235117299.1 tRNA-modifying protein YgfZ -
NFJ24_RS04120 (849125) 849125..849391 + 267 WP_016154349.1 FAD assembly factor SdhE Antitoxin
NFJ24_RS04125 (849372) 849372..849779 + 408 WP_047357821.1 protein YgfX Toxin
NFJ24_RS04130 (849880) 849880..850401 - 522 WP_016154347.1 flavodoxin FldB -
NFJ24_RS04135 (850515) 850515..851411 + 897 WP_016154346.1 site-specific tyrosine recombinase XerD -
NFJ24_RS04140 (851435) 851435..852148 + 714 WP_103766660.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFJ24_RS04145 (852154) 852154..853887 + 1734 WP_016157413.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15878.67 Da        Isoelectric Point: 11.5023

>T248844 WP_047357821.1 NZ_CP099389:849372-849779 [Citrobacter braakii]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWTIASAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLILQQARQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.10 Da        Isoelectric Point: 5.6375

>AT248844 WP_016154349.1 NZ_CP099389:849125-849391 [Citrobacter braakii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7L6TYP6

Antitoxin

Source ID Structure
AlphaFold DB R8WMJ6

References