Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4258787..4259306 Replicon chromosome
Accession NZ_CP099386
Organism Citrobacter braakii strain RHB09-E4-C01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFJ61_RS20375 Protein ID WP_019078244.1
Coordinates 4258787..4259068 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFJ61_RS20380 Protein ID WP_137380106.1
Coordinates 4259058..4259306 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ61_RS20360 (4255788) 4255788..4256252 + 465 WP_016151476.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFJ61_RS20365 (4256274) 4256274..4256795 - 522 WP_279272503.1 hypothetical protein -
NFJ61_RS20370 (4256795) 4256795..4258759 - 1965 WP_279272504.1 type VI secretion system tip protein TssI/VgrG -
NFJ61_RS20375 (4258787) 4258787..4259068 - 282 WP_019078244.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFJ61_RS20380 (4259058) 4259058..4259306 - 249 WP_137380106.1 plasmid stabilization protein Antitoxin
NFJ61_RS20385 (4259404) 4259404..4259532 - 129 WP_016155557.1 hypothetical protein -
NFJ61_RS20390 (4259601) 4259601..4260074 - 474 WP_016155556.1 hypothetical protein -
NFJ61_RS20395 (4260117) 4260117..4262618 - 2502 WP_279272505.1 type VI secretion system ATPase TssH -
NFJ61_RS20400 (4262609) 4262609..4263556 - 948 WP_047414725.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10988.76 Da        Isoelectric Point: 10.4466

>T248820 WP_019078244.1 NZ_CP099386:c4259068-4258787 [Citrobacter braakii]
MTYNLEFLDIALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9045.31 Da        Isoelectric Point: 4.5680

>AT248820 WP_137380106.1 NZ_CP099386:c4259306-4259058 [Citrobacter braakii]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELAEDAELNRIADEREDGKRIKVSLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References