Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 799056..799710 Replicon chromosome
Accession NZ_CP099386
Organism Citrobacter braakii strain RHB09-E4-C01

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFJ61_RS03925 Protein ID WP_151222347.1
Coordinates 799303..799710 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID R8WMJ6
Locus tag NFJ61_RS03920 Protein ID WP_016154349.1
Coordinates 799056..799322 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ61_RS03895 (794270) 794270..795703 - 1434 WP_279272683.1 6-phospho-beta-glucosidase BglA -
NFJ61_RS03900 (795823) 795823..796551 - 729 WP_003838265.1 MurR/RpiR family transcriptional regulator -
NFJ61_RS03905 (796604) 796604..796915 + 312 WP_016154352.1 N(4)-acetylcytidine aminohydrolase -
NFJ61_RS03910 (797079) 797079..797738 + 660 WP_016154351.1 hemolysin III family protein -
NFJ61_RS03915 (797818) 797818..798798 - 981 WP_016154350.1 tRNA-modifying protein YgfZ -
NFJ61_RS03920 (799056) 799056..799322 + 267 WP_016154349.1 FAD assembly factor SdhE Antitoxin
NFJ61_RS03925 (799303) 799303..799710 + 408 WP_151222347.1 protein YgfX Toxin
NFJ61_RS03930 (799811) 799811..800332 - 522 WP_016154347.1 flavodoxin FldB -
NFJ61_RS03935 (800446) 800446..801342 + 897 WP_016154346.1 site-specific tyrosine recombinase XerD -
NFJ61_RS03940 (801366) 801366..802079 + 714 WP_016154345.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFJ61_RS03945 (802085) 802085..803818 + 1734 WP_049269301.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15892.70 Da        Isoelectric Point: 11.5023

>T248812 WP_151222347.1 NZ_CP099386:799303-799710 [Citrobacter braakii]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWTIASAPWMIKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLILQQARQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.10 Da        Isoelectric Point: 5.6375

>AT248812 WP_016154349.1 NZ_CP099386:799056-799322 [Citrobacter braakii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB R8WMJ6

References