Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2879992..2880582 Replicon chromosome
Accession NZ_CP099384
Organism Citrobacter braakii strain RHB13-SO-C07

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag NFJ78_RS13820 Protein ID WP_049041157.1
Coordinates 2879992..2880324 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag NFJ78_RS13825 Protein ID WP_049041154.1
Coordinates 2880325..2880582 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ78_RS13795 (2875028) 2875028..2875387 - 360 WP_016156204.1 purine nucleoside phosphoramidase -
NFJ78_RS13800 (2875736) 2875736..2877922 + 2187 WP_181634828.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
NFJ78_RS13810 (2878257) 2878257..2879744 + 1488 WP_279262445.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
NFJ78_RS13820 (2879992) 2879992..2880324 - 333 WP_049041157.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NFJ78_RS13825 (2880325) 2880325..2880582 - 258 WP_049041154.1 antitoxin Antitoxin
NFJ78_RS13830 (2881193) 2881193..2885092 + 3900 WP_279262446.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11731.54 Da        Isoelectric Point: 8.5572

>T248792 WP_049041157.1 NZ_CP099384:c2880324-2879992 [Citrobacter braakii]
MDRGEIWLVSLDPTAGHEQSGKRPVLIVSPASFNKFTRLPVVVPVTSGGNFARAAGFTVSLDGVGTKTTGVIRCDQPRTI
DMGARNGKCLERIPEAVVNEVLARLEAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9370.85 Da        Isoelectric Point: 4.4354

>AT248792 WP_049041154.1 NZ_CP099384:c2880582-2880325 [Citrobacter braakii]
MYTTRLKKVGGSIMLAVPPAVLKTLALSTDSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSDEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References