Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 687753..688432 Replicon chromosome
Accession NZ_CP099384
Organism Citrobacter braakii strain RHB13-SO-C07

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag NFJ78_RS03325 Protein ID WP_222186296.1
Coordinates 688091..688432 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NFJ78_RS03320 Protein ID WP_222186295.1
Coordinates 687753..688070 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ78_RS03280 (683134) 683134..684081 + 948 WP_222186287.1 ankyrin repeat domain-containing protein -
NFJ78_RS03285 (684247) 684247..685110 + 864 WP_222186288.1 GTPase family protein -
NFJ78_RS03290 (685202) 685202..685612 + 411 Protein_645 DUF932 domain-containing protein -
NFJ78_RS03295 (685667) 685667..686140 + 474 WP_222186292.1 hypothetical protein -
NFJ78_RS03300 (686218) 686218..686457 + 240 WP_222186293.1 DUF905 domain-containing protein -
NFJ78_RS03305 (686554) 686554..687012 + 459 WP_222186294.1 antirestriction protein -
NFJ78_RS03310 (687028) 687028..687504 + 477 WP_218733310.1 RadC family protein -
NFJ78_RS03315 (687513) 687513..687734 + 222 WP_218733312.1 DUF987 domain-containing protein -
NFJ78_RS03320 (687753) 687753..688070 + 318 WP_222186295.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ78_RS03325 (688091) 688091..688432 + 342 WP_222186296.1 TA system toxin CbtA family protein Toxin
NFJ78_RS03330 (688549) 688549..689382 + 834 WP_222186297.1 DUF4942 domain-containing protein -
NFJ78_RS03340 (689686) 689686..690192 + 507 WP_019077714.1 G/U mismatch-specific DNA glycosylase -
NFJ78_RS03345 (690238) 690238..692082 - 1845 WP_016154549.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-110)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12842.87 Da        Isoelectric Point: 8.9788

>T248785 WP_222186296.1 NZ_CP099384:688091-688432 [Citrobacter braakii]
MKTLPATTPQAAKLCLPPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGITLADAVNFLVDKYELVRIDRKGF
SWQEQSPYLRAVDILRARQATGLLRQSRNKPVR

Download         Length: 342 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12027.66 Da        Isoelectric Point: 7.3227

>AT248785 WP_222186295.1 NZ_CP099384:687753-688070 [Citrobacter braakii]
MSNITWGLRRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECRKLDETFPHFISQMESMLTTYELNPRHAHCVILYH
NGFTCEADTLGSCGYVYVAVYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References