248783

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4535991..4536510 Replicon chromosome
Accession NZ_CP099382
Organism Citrobacter braakii strain RHB14-SO-C08

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFJ83_RS21800 Protein ID WP_019078244.1
Coordinates 4535991..4536272 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFJ83_RS21805 Protein ID WP_103283421.1
Coordinates 4536262..4536510 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ83_RS21785 (4532992) 4532992..4533456 + 465 WP_016151476.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFJ83_RS21790 (4533478) 4533478..4533999 - 522 WP_049270665.1 hypothetical protein -
NFJ83_RS21795 (4533999) 4533999..4535963 - 1965 WP_279265956.1 type VI secretion system tip protein TssI/VgrG -
NFJ83_RS21800 (4535991) 4535991..4536272 - 282 WP_019078244.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFJ83_RS21805 (4536262) 4536262..4536510 - 249 WP_103283421.1 plasmid stabilization protein Antitoxin
NFJ83_RS21810 (4536608) 4536608..4536736 - 129 WP_016155557.1 hypothetical protein -
NFJ83_RS21815 (4536805) 4536805..4537278 - 474 WP_016155556.1 hypothetical protein -
NFJ83_RS21820 (4537321) 4537321..4539822 - 2502 WP_279265957.1 type VI secretion system ATPase TssH -
NFJ83_RS21825 (4539813) 4539813..4540760 - 948 WP_103284439.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10988.76 Da        Isoelectric Point: 10.4466

>T248783 WP_019078244.1 NZ_CP099382:c4536272-4535991 [Citrobacter braakii]
MTYNLEFLDIALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9073.37 Da        Isoelectric Point: 4.5680

>AT248783 WP_103283421.1 NZ_CP099382:c4536510-4536262 [Citrobacter braakii]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELVEDAELNRIADEREDGKRIKVSLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References