248774

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 876684..877338 Replicon chromosome
Accession NZ_CP099382
Organism Citrobacter braakii strain RHB14-SO-C08

Toxin (Protein)


Gene name cptA Uniprot ID R8WN60
Locus tag NFJ83_RS04315 Protein ID WP_016154348.1
Coordinates 876931..877338 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID R8WMJ6
Locus tag NFJ83_RS04310 Protein ID WP_016154349.1
Coordinates 876684..876950 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ83_RS04285 (871897) 871897..873330 - 1434 WP_016154353.1 6-phospho-beta-glucosidase BglA -
NFJ83_RS04290 (873451) 873451..874179 - 729 WP_103284472.1 MurR/RpiR family transcriptional regulator -
NFJ83_RS04295 (874232) 874232..874543 + 312 WP_016154352.1 N(4)-acetylcytidine aminohydrolase -
NFJ83_RS04300 (874707) 874707..875366 + 660 WP_016154351.1 hemolysin III family protein -
NFJ83_RS04305 (875446) 875446..876426 - 981 WP_016154350.1 tRNA-modifying protein YgfZ -
NFJ83_RS04310 (876684) 876684..876950 + 267 WP_016154349.1 FAD assembly factor SdhE Antitoxin
NFJ83_RS04315 (876931) 876931..877338 + 408 WP_016154348.1 protein YgfX Toxin
NFJ83_RS04320 (877439) 877439..877960 - 522 WP_016154347.1 flavodoxin FldB -
NFJ83_RS04325 (878074) 878074..878970 + 897 WP_016154346.1 site-specific tyrosine recombinase XerD -
NFJ83_RS04330 (878994) 878994..879707 + 714 WP_075847456.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFJ83_RS04335 (879713) 879713..881446 + 1734 WP_103284192.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15850.66 Da        Isoelectric Point: 11.2845

>T248774 WP_016154348.1 NZ_CP099382:876931-877338 [Citrobacter braakii]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWTIASAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLILQQAKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.10 Da        Isoelectric Point: 5.6375

>AT248774 WP_016154349.1 NZ_CP099382:876684-876950 [Citrobacter braakii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB R8WN60

Antitoxin

Source ID Structure
AlphaFold DB R8WMJ6

References