Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4362344..4363024 Replicon chromosome
Accession NZ_CP099381
Organism Citrobacter braakii strain RHB16-E2-C02

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFJ84_RS21005 Protein ID WP_279265310.1
Coordinates 4362344..4362664 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFJ84_RS21010 Protein ID WP_279265311.1
Coordinates 4362701..4363024 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ84_RS20975 (NFJ84_20955) 4357712..4358197 - 486 WP_094760967.1 type VI secretion system tube protein TssD -
NFJ84_RS20980 (NFJ84_20960) 4358217..4358549 - 333 WP_094760968.1 DUF1493 family protein -
NFJ84_RS20985 (NFJ84_20965) 4358543..4358998 - 456 WP_235117079.1 hypothetical protein -
NFJ84_RS20990 (NFJ84_20970) 4359257..4360129 + 873 WP_047500815.1 HNH endonuclease -
NFJ84_RS20995 (NFJ84_20975) 4360316..4361323 - 1008 WP_279265308.1 restriction endonuclease -
NFJ84_RS21000 (NFJ84_20980) 4361400..4362230 - 831 WP_279265309.1 DUF4942 domain-containing protein -
NFJ84_RS21005 (NFJ84_20985) 4362344..4362664 - 321 WP_279265310.1 TA system toxin CbtA family protein Toxin
NFJ84_RS21010 (NFJ84_20990) 4362701..4363024 - 324 WP_279265311.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ84_RS21015 (NFJ84_20995) 4363037..4363507 - 471 WP_279265312.1 DNA repair protein RadC -
NFJ84_RS21020 (NFJ84_21000) 4363579..4364397 - 819 WP_279265313.1 DUF932 domain-containing protein -
NFJ84_RS21025 (NFJ84_21005) 4364547..4365344 - 798 WP_279265314.1 hypothetical protein -
NFJ84_RS21030 (NFJ84_21010) 4365788..4366672 - 885 WP_279265315.1 50S ribosome-binding GTPase -
NFJ84_RS21035 (NFJ84_21015) 4366871..4367725 - 855 WP_279265316.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4358217..4376805 18588


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12011.68 Da        Isoelectric Point: 6.3221

>T248771 WP_279265310.1 NZ_CP099381:c4362664-4362344 [Citrobacter braakii]
MHISSVPPTVPVSSRLSPVQVWKQLLTYLLEHHYGLTLNDTPFHDGAAIEDHIDAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLTTTDILRARRATGLINT

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12015.84 Da        Isoelectric Point: 6.8489

>AT248771 WP_279265311.1 NZ_CP099381:c4363024-4362701 [Citrobacter braakii]
MSITPPHEWGLQSDITPRFGARLVQEGNRLYYPADRAGLMGSFSPIHLQKLDLAFPLFVEKLENMLRAGELNPHQQHQVT
IQLASLTCIADTRGCCGYVYISIYPTP

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References