Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4233044..4233563 Replicon chromosome
Accession NZ_CP099378
Organism Citrobacter braakii strain RHB21-E1-C04

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFK10_RS20365 Protein ID WP_016155559.1
Coordinates 4233044..4233325 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0V9JX71
Locus tag NFK10_RS20370 Protein ID WP_016155558.1
Coordinates 4233315..4233563 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK10_RS20350 (4230048) 4230048..4230512 + 465 WP_016155562.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFK10_RS20355 (4230531) 4230531..4231052 - 522 WP_016155561.1 hypothetical protein -
NFK10_RS20360 (4231052) 4231052..4233016 - 1965 WP_279278345.1 type VI secretion system tip protein TssI/VgrG -
NFK10_RS20365 (4233044) 4233044..4233325 - 282 WP_016155559.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFK10_RS20370 (4233315) 4233315..4233563 - 249 WP_016155558.1 hypothetical protein Antitoxin
NFK10_RS20375 (4233661) 4233661..4233789 - 129 WP_016155557.1 hypothetical protein -
NFK10_RS20380 (4233858) 4233858..4234331 - 474 WP_016155556.1 hypothetical protein -
NFK10_RS20385 (4234374) 4234374..4236875 - 2502 WP_016155555.1 type VI secretion system ATPase TssH -
NFK10_RS20390 (4236866) 4236866..4237813 - 948 WP_016155554.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11004.76 Da        Isoelectric Point: 10.4466

>T248750 WP_016155559.1 NZ_CP099378:c4233325-4233044 [Citrobacter braakii]
MTYNLEFLDVALKEWRKLSPTLREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8987.28 Da        Isoelectric Point: 4.7513

>AT248750 WP_016155558.1 NZ_CP099378:c4233563-4233315 [Citrobacter braakii]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELAEDAELNRIADEREGGKRIKVSLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0V9JX71

References